BK Polyomavirus in Pediatric Renal Transplantation—What We Know and What We Do Not
Benedetta Chiodini,
Pauline Guillaume-Gentil,
Charlotte Vanhomwegen
et al.
Abstract:BK polyomavirus (BKPyV) is still a real threat in the management of kidney transplantation. Immunosuppressive treatment disrupts the equilibrium between virus replication and immune response, and uncontrolled BKPyV replication leads to nephropathy (BKPyV nephropathy). The first evidence of BKPyV reactivation in transplant recipients is the detection of viral shedding in urine, which appears in 20% to 60% of patients, followed by BKPyV viremia in 10–20% of kidney transplant recipients. BKPyV nephropathy eventua… Show more
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