Black Hairy Tongue Associated With Olanzapine Use in a Female Dementia Patient

Long, Siwei; Chen, Yajing; Shi, Jing; Tian, Jinzhou; Ni, Jingnian

doi:10.1097/jcp.0000000000001503

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2022

2023

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Cited by 3 publications

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“…The underlying predisposing factors of tongue discoloration include smoking, poor oral hygiene, psychotropics (eg, olanzapine), antibiotics (eg, tetracyclines, metronidazole). [12][13][14] Differential diagnoses include oral hairy leukoplakia, acanthosis nigricans, pigmented fungiform papillae, melanocytic nevi, and pseudo BHT (like food coloring). 9 Dermoscopy can help to confirm.…”

Section: Discussionmentioning

confidence: 99%

Oral Bacteria Dysbiosis in Patients with Linezolid-Induced Black Hairy Tongue: A Case Series

Shangguan¹,

Ji²,

Guo³

et al. 2022

IDR

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Linezolid-induced black hairy tongue is a self-limiting benign disease that is rare. Here, we report three patients who developed black hairy tongue after linezolid treatment. The severe dysbiosis of oral bacterial communities was observed in all these patients. Proteobacteria was the most prevalent phylum (over 90%) at the black tongue stage. Furthermore, the dramatic oral bacterial alteration took a long time to reverse after the BHT resolved.

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