Bladder Cancer: Analysis of Multi–Detector Row Helical CT Enhancement Pattern and Accuracy in Tumor Detection and Perivesical Staging

Kim, Jeong Kon; Park, Soo-Youn; Ahn, Hyung Taek; Kim, Chung Soo; Cho, Kyoung-Sik

doi:10.1148/radiol.2313021253

Cited by 177 publications

(91 citation statements)

References 16 publications

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“…They are classified into autosomal diseases, when the gene is not located on the sex chromosomes, and X-linked, in the case in which the disease gene is localized in the female sex chromosome. (23,24,25,26)They are also divided into dominant and recessive diseases, depending on which is sufficient only one copy or two copies of the mutated gene to determine the disease. d) multifactorial or complex.…”

Section: Discussion:-mentioning

confidence: 99%

Congenital Anomalies of the Kidney and Urinary Tract Neoplasms and in the Elderly.

G¹,

Cataldo.²

2017

IJAR

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Introduction: Congenital abnormalities of the kidneys and urinary tract represented a spectrum of malformations often grouped under the acronym for CAKUT. Normal development of the kidneys and urinary tract is the result of the precise interaction, spatially and temporally coordinated, between two structures, the metanephric mesenchyme (which originates from the nephrogenic cord) and the ureteric bud (which originates from nefrico duct or Wolff). Any alteration, it's genetic, environmental, or stochastic, which influence this process can result in kidney malformations and streets urinariedel present study is to evaluate in relation to clinical attention the incidence of risk in neoplastic 'association cancer and malformation. in adults Materials end Methods: Male patient of 75 suffering from gross hematuria and hernia inquinale sn accompanied by dysuria symptoms, in heavy smoker instrumental ultrasound examination of the urinary tract showed a solid lesion in the posterolateral wall sn aggittante in the bladder lumen The uro-CT examination showed a " abnormality of the urinary tract development with ectopia crusade and merger of the two kidneys located alongside sn (fot, 3.4) of the renal pelvis are addressed before the district complete with double ureteral sn .In at the urethral meatus will highlight a focal thickening protruding into the lumen wall to finely irregular margins, with enhancement after contrast medium. (photo 5.6) the CT examination conducted in the chest (photo 7) confirmed the marked signs of emphysema, the anterior segment of the left upper lobe, in close relationship with bronchus and vessels segmented solid training in margins lobed (29x20 mm axial diameter approximately). At PET-CT accumulation of the tracer in the upper field of the left lung in the paramedian attributable to non-specific reactive process . Fig (8.9), then he performed genetic test that confirmed mutations in the PAX2 Results: The UroCT is the imaging examination with greater sensitivity and specificity. The limit lies in the poor ability to detect flat lesions non-invasive muscle. The urography has been almost entirely supplanted by UroTC. The current biomarkers do not have a sensitivity and specificity greater than urinary cytology, and The aromatic amines, NAT2 and NAT1 of tobacco smoking products, are considered the

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Section: Discussion:-mentioning

confidence: 99%

Congenital Anomalies of the Kidney and Urinary Tract Neoplasms and in the Elderly.

G¹,

Cataldo.²

2017

IJAR

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“…Tumoural neovascularisation can be evaluated using imaging modalities after the administration of contrast agents and bladder cancer is a hypervascular tumour that shows strong enhancement in the arterial phase, followed by a plateau of enhancement and a slow washout when evaluated with imaging modalities after the administration of contrast agents [14,[17][18][19]. Despite conventional ultrasound currently being the preferred non-invasive imaging technique for the screening of bladder cancers, its accuracy depends on several factors, including distension of the bladder, tumour size, morphology and location of the lesions [2].…”

Section: Discussionmentioning

confidence: 99%

Accuracy of contrast-enhanced ultrasound in the detection of bladder cancer

Nicolau¹,

Buñesch²,

Peri³

et al. 2011

BJR

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Objective: To assess the accuracy contrast-enhanced ultrasound (CEUS) in bladder cancer detection using transurethral biopsy in conventional cystoscopy as the reference standard and to determine whether CEUS improves the bladder cancer detection rate of baseline ultrasound. Methods: 43 patients with suspected bladder cancer underwent conventional cystoscopy with transurethral biopsy of the suspicious lesions. 64 bladder cancers were confirmed in 33 out of 43 patients. Baseline ultrasound and CEUS were performed the day before surgery and the accuracy of both techniques for bladder cancer detection and number of detected tumours were analysed and compared with the final diagnosis. Results: CEUS was significantly more accurate than ultrasound in determining presence or absence of bladder cancer: 88.37% vs 72.09%. Seven of eight uncertain baseline ultrasound results were correctly diagnosed using CEUS. CEUS sensitivity was also better than that of baseline ultrasound per number of tumours: 65.62% vs 60.93%. CEUS sensitivity for bladder cancer detection was very high for tumours larger than 5 mm (94.7%) but very low for tumours ,5 mm (20%) and also had a very low negative predictive value (28.57%) in tumours ,5 mm. Conclusion: CEUS provided higher accuracy than baseline ultrasound for bladder cancer detection, being especially useful in non-conclusive baseline ultrasound studies.

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“…58 The staging for primary disease in UCB consists of abdomen and pelvis CT with contrast, including delayed images to identify defects in the collecting system (CT urography). 59 Gadolinium-enhanced magnetic resonance imaging (MRI) of the pelvis displays comparable accuracy to CT for finding non-organ confined bladder cancer, 60,61 however, MRI has a higher sensitivity for extra-vesical tumour extension and adjacent organ invasion. 62 Therefore, MRI may be helpful if radical cystectomy is being considered.…”

Section: Staging Investigationsmentioning

confidence: 99%

Management of small cell carcinoma of the bladder: Consensus guidelines from the Canadian Association of Genitourinary Medical Oncologists (CAGMO)

Moretto

Wood

Emmenegger

et al. 2013

CUAJ

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Bladder Cancer: Analysis of Multi–Detector Row Helical CT Enhancement Pattern and Accuracy in Tumor Detection and Perivesical Staging

Abstract: Bladder cancer tends to show peak enhancement with the 60-second scanning delay. Multi-detector row helical CT is useful in the detection and staging of bladder cancer.

Cited by 177 publications

References 16 publications

Congenital Anomalies of the Kidney and Urinary Tract Neoplasms and in the Elderly.

Congenital Anomalies of the Kidney and Urinary Tract Neoplasms and in the Elderly.

Accuracy of contrast-enhanced ultrasound in the detection of bladder cancer

Management of small cell carcinoma of the bladder: Consensus guidelines from the Canadian Association of Genitourinary Medical Oncologists (CAGMO)

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