Bladder cancer with obstructive uremia: Oncologic outcome after definitive surgical management

One-Step In Situ Self-Assembly of Biodegradable Films for Long-Term Intravesical Bladder Cancer Therapy

“…The volume of tumors in mice treated with GEM alone decreased significantly at 3 day post-treatment, but it still increased rapidly after day 7, showing the insufficient ongoing effect of GEM on tumor regression. Meanwhile, the tumor growth rate in the TA@Fe-treated group was moderately slower than that in the untreated control group, which could be ascribed to the anticancer effect of TA. − Such a short survival time for BC may be due to uremia caused by poor urination . The enhanced therapeutic efficacy of the GEM-loaded TA@Fe film was further revealed by H&E and immunohistochemical images, which in turn demonstrated the reliability of MRI results (Figures b and S11).…”

“…29−31 Such a short survival time for BC may be due to uremia caused by poor urination. 32 The enhanced therapeutic efficacy of the GEMloaded TA@Fe film was further revealed by H&E and immunohistochemical images, which in turn demonstrated the reliability of MRI results (Figures 4b and S11). Traditional intravesical chemotherapy with GEM alone successfully reduced the volume of the tumor and inhibited the growth of the tumor at 3 days, but the tumor quickly returned to growth after 3 days, which may be attributed to the short retention time of GEM in the bladder (Figure 4c).…”

Clinical features of bladder cancer in primary care

“…28 It cannot be determined if the patients had obstructive nephropathy, to account for the higher percentage of cases in this study with raised creatinine.…”

Percutaneous Nephrostomy in Patients with Tumors of Advanced Stage: Treatment Dilemmas and Impact on Clinical Course and Quality of Life

“…1,6,10 In a majority of advanced neoplasm examples, survival rates are significantly poor even after urinary diversion, especially if largely disseminated or recurrent disease has occurred. 1,5,[11][12][13][14][15] Our decision to use two tumor load subgroups of disease extent throughout the variety of neoplasms in our study was based on the fact that urologic malignancies may be expected to produce severe obstruction earlier or in lower tumor volumes. By defining locally advanced and largely disseminated (including metastatic) disease, we thought that we could avoid this bias and improve the objectivity of our comparisons.…”