Bladder hypocontractility—extending the indication for LDDM

Gakis, Georgios; Ninković, Milomir; Stenzl, Arnulf

doi:10.1038/nrurol.2011.27-c1

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…The muscle is the wrapped around the bladder and anchored to the pelvic floor. Gakis et al reported the long‐term outcomes of these patients in 2011. All 24 patients with AcB were catheter dependent.…”

Section: Managementmentioning

confidence: 99%

Current concepts of the acontractile bladder

et al. 2018

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The acontractile bladder (AcB) is a urodynamic-based diagnosis wherein the bladder is unable to demonstrate any contraction during a pressure flow study. Although it is often grouped with underactive bladder, it is a unique phenomenon and should be investigated independently. The purpose of the present review was to examine the current literature on AcB regarding its pathology, diagnosis, current management guidelines, and future developments. We performed a review of the PubMed database, classifying the evidence for AcB pathology, diagnosis, treatment, and potential future treatments. Over the 67 years covered in our review period, 42 studies were identified that met our criteria. Studies were largely poor quality and mainly consisted of retrospective review or animal models. The underlying pathology of AcB is variable with both neurological and myogenic aetiologies. Treatment is largely tailored for renal preservation and reduction of infection. Although future developments may allow more functional restorative treatments, current treatments mainly focus on bladder drainage. AcB is a unique and understudied bladder phenomenon. Treatment is largely based on symptoms and presentation. While cellular therapy and neuromodulation may hold promise, further research is needed into the underlying neuro-urological pathophysiology of this disease so that we may better develop future treatments.

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Section: Managementmentioning

confidence: 99%

Current concepts of the acontractile bladder

et al. 2018

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Latissimus Dorsi Detrusor Myoplasty to Restore Voiding in Patients with an Acontractile Bladder – Fact or Fiction?

2013

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Multiple causes at any level between the brain and the bladder can lead to diminished voiding efficiency and bladder acontractility. Treatment options for patients with an acontractile bladder have been limited as most patients were forced to perform lifelong self-catheterization at the moment. The latissimus dorsi detrusor myoplasty (LDDM) is a recent and promising therapeutic surgical option to restore adequate bladder emptying on demand. This article critically reviews the available literature on LDDM and focuses particularly on the preoperative diagnostic evaluation and patient selection, treatment outcome and the postoperative contractility measurement.

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Bladder hypocontractility—extending the indication for LDDM

Cited by 2 publications

References 10 publications

Current concepts of the acontractile bladder

Current concepts of the acontractile bladder

Latissimus Dorsi Detrusor Myoplasty to Restore Voiding in Patients with an Acontractile Bladder – Fact or Fiction?

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