Bladder sensations in male and female overactive bladder patients compared to healthy volunteers: a sensation-related bladder diary evaluation

Abstract

Objectives: To investigate the differences in bladder sensations of overactive bladder (OAB) patients compared to healthy volunteers. In addition, to see if bladder sensations are different in men and women. Methods: In a prospective, longitudinal study (METC 09-2-095), 66 volunteers and 68 OAB patients were included. Anticholinergic medication was stopped. Subjects filled out a sensation-related bladder diary (SR-BD), for two periods of 3 days, including a 4-points urgency scale and visual analogue scale for perception of bladder fullness. Results: In total, 6160 voids were assessed. Patients voided more often with higher degrees of urge at a lower mean voided volume (193 vs 270 ml/void; p < 0.001) than healthy volunteers. The mean urinary frequency per litre diuresis was also higher (5.8 vs 4.1/l; p < 0.001) in patients. At the same voided volume: patients perceived a higher mean bladder fullness, independent of the degree of urge, and higher urgency (1.4 vs 0.5/100 ml; p < 0.001) than healthy volunteers. There were no gender differences in the above-mentioned voiding parameters, except for the mean voided volume at urge 3 in volunteers (340 ml in men vs 362 ml in women; p ¼ 0.03) and urge 1 in patients (171 ml in men vs 135 ml in women; p ¼ 0.027). Conclusions: Bladder sensations were significantly increased in everyday life for both male and female OAB patients compared to healthy volunteers. OAB patients experienced a higher mean bladder fullness sensation, independent of the degree of urge, and higher mean urge/urgency at the same voided volume than volunteers. Bladder sensations are crucial in the assessment of treatment response. ARTICLE HISTORY

Comparative Study Between Bladder Diary and Urodynamic Study to Identify Lower Urinary Tract Symptoms

“…When identified by the clinic, without confirmation by the UDS, it is called overactive bladder. Patients with DO or overactive bladder had a greater perception of fullness and urgency for the same volume urinated when compared to healthy volunteers 14 , so that these patients have less bladder capacity 21 . It is noteworthy that at least five other patients had suspected DO, which was not confirmed.…”

“…A conservative and low-cost way to assess urinary pattern and symptoms is the bladder diary (BD), a noninvasive tool used to assess bladder sensations on a daily basis. Besides urinary frequency and volume, it also includes the degree of desire and the perception of the fullness of the bladder before emptying, and is considered an important tool for the diagnosis of voiding dysfunction 14 . This instrument is filled out by the patients themselves or by a caregiver and can be oriented by any health professional who works with people who present with urinary complaints.…”

Estudo Comparativo Entre Diário Vesical E Estudo Urodinâmico Para Identificação De Sintomas Do Trato Urinário Inferior

“…Quando identificada pela clínica, sem confirmação pelo EU, é denominada de bexiga hiperativa. Pacientes com HD ou bexiga hiperativa apresentaram maior percepção de plenitude e urgência para o mesmo volume urinado quando comparados a voluntários saudáveis 14 , de modo que esses pacientes apresentam capacidade vesical menor 21 . Vale ressaltar que pelo DV outros cinco pacientes tinham suspeita de HD, que não foi confirmada.…”

“…Uma maneira conservadora e de baixo custo para avaliar padrão e sintomas urinários é a aplicação de diário vesical (DV), uma ferramenta não invasiva usada para avaliar as sensações da bexiga no dia a dia. Além da frequência urinária e do volume, também incluindo o grau de desejo e a percepção da plenitude da bexiga antes de esvaziar, é considerado um importante instrumento para o diagnóstico de disfunção miccional 14 . Esse instrumento é preenchido pelo próprio paciente ou por um cuidador e pode ser orientado por qualquer profissional de saúde que trabalhe com pessoas que apresentam queixas urinárias.…”