Recently, reported long-term climate change consequences, such as rising temperatures and melting glaciers, have emphasized mitigation and adaptation actions. While moderating the severity of climate changes, precautionary human actions can also protect the natural environment and human societies. Furthermore, public and private collaboration can leverage resources and expertise, resulting in more impactful mitigation and adaptation actions for effective climate change responses. A coordinated and strategic approach is necessary in order to prioritize these actions across different scales, enabling us to maximize the benefits of climate action and ensure a coordinated response to this global challenge. This study examines the interplay between climate mitigation and adaptation actions in Greece and the European Union (EU). We conducted a literature search using relevant keywords. The search results were systematically approached in alignment with two pairs of thematic homologous entities, enabling the review of these literature findings to be organized and holistically investigated. In this respect, the three fields of agriculture, energy, and multi-parametric determinants of climate neutrality have emerged and been discussed. Our analysis also focused on the key implemented and planned mitigation and adaptation climate actions. Through this review, we identified the most important motives and challenges related to joint adaptation and mitigation actions. Our findings underscore the need for a comprehensive approach to climate action planning that incorporates both adaptation and mitigation measures.