Blastomycosis in Animals

Safety, Tolerability, and Immunogenicity of a Recombinant, Genetically Engineered, Live-Attenuated Vaccine against Canine Blastomycosis

“…Rectal temperature, size of the draining lymph node, and swelling of the injection site were evaluated by a veterinarian blinded to the identities of the treatment groups. Evaluations were done 2,5,7,9,12,14,16,19,24, and 26 days after the first injection of vaccine. Swelling or nodules in the area were evaluated by picking up a skin fold that contained the injection site.…”

“…In dogs, the fungus often disseminates from the lungs to the skin, eyes, lymph nodes, and bones. The mortality rate exceeds 90% for dogs that do not receive prompt antifungal treatment (9). Blastomycosis is most commonly seen in large dogs, where the cost of treatment can exceed $1,000.…”

Blastomycosis

“…Other mammals, especially dogs, may become infected [27]. Early studies of endemic cases suggested middle-aged men with outdoor occupations were at greatest risk for blastomycosis.…”

Blastomycosis in six dogs in New York state

“…There are several reports of dogs and their owners being infected simultaneously with B dermatitidis, 3 and veterinarians should prompt owners of infected dogs to be more vigilant about their own health and to consult a physician if necessary The owners of dogs 1,2, and 3 and their families were examined by their physicians and treatment was not deemed necessary A previous report specifically describes 6 cases in which a veterinarian's diagnosis of blastomycosis was responSible for the initial suspicion and subsequent early diagnosis and treatment of blastomycosis in owners or neighbors of affected animalsY The vigilance of veterinarians may be particularly important in areas, as in this report, in which blastomycosis is sporadic. The incidence of blastomycosis is approximately 10 times greater in dogs than in people 18 and because people and dogs can be infected at the same source, dogs are considered a sentinel for human disease.…”