Bleds

Pd-Oxazolone complexes conjugated to an engineered enzyme: improving fluorescence and catalytic properties

“…The oxazolones 1a and 1b were synthesized by the Erlenmeyer-Plöchl method as reported. [16][17][18][19][20][21][22][23][24][25] They were selected as complex scaffolds due to their push-pull electronic nature, which enhances charge separation and luminescence properties, and also because of their different steric requirements (Fig. S1 †).…”

“…Infrared spectra were recorded on a Spectrum 100 PerkinElmer FTIR Spectrophotometer, with a Universal Attenuated Total Reflectance (UATR) accessory (4000-250 cm −1 ). The 1 H, 13 C{ 1 H} and 19 F NMR spectra were recorded on a Bruker Avance-300 spectrometer (δ in ppm; J in Hz). All experiments were recorded on solution at room temperature using CD 2 Cl 2 or CDCl 3 as the deuterated solvents.…”

“…Other conditions were specified on each particular case. The 1 H and 13 C{ 1 H} spectra were referenced using the residual solvent signal as internal standard, while 19 F spectra were referenced to CFCl 3 . The N-cinnamoylglycine used for the synthesis of 1b was prepared by the Schotten-Baumann method.…”