Blei und seine Verbindungen (außer Bleiarsenat, Bleichromat und Alkylbleiverbindungen) [BAT Value Documentation in German language, 2001]

Bolt, Hermann M.; Schaller, K. H.

doi:10.1002/3527600418.bb743992d0010

The MAK‐Collection for Occupational Health and Safety 2012

DOI: 10.1002/3527600418.bb743992d0010

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Blei und seine Verbindungen (außer Bleiarsenat, Bleichromat und Alkylbleiverbindungen) [BAT Value Documentation in German language, 2001]

Hermann M. Bolt¹,

K. H. Schaller²

Abstract: Veröffentlicht in der Reihe Biologische Arbeitsstoff‐Toleranz‐Werte (BAT‐Werte) und Expositionsäquivalente für krebserzeugende Arbeitsstoffe (EKA) , 10. Lieferung, Ausgabe 2001 Der Artikel enthält folgende Kapitel: Angaben zur Pharmakokinetik Resorption Elimination Stofftwechsel Kritische Tox… Show more

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2018

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Cited by 2 publications

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Blei und seine Verbindungen – Bestimmung vonδ‐Aminolävulinsäure in Urin mittels HPLC‐Fluoreszenzdetektion [Biomonitoring Methods in German language, 2018]

Hartwig¹,

Arand²

2018

The MAK‐Collection for Occupational Health and Safety

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The working group “Analyses in Biological Materials” of the Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area verified the presented biomonitoring method. The method described hereinafter permits the determination of δ ‐aminolevulinic acid (ALA) in urine as a biological marker of effect to assess exposure to lead. An indicator of such exposure is the increased urinary excretion of ALA caused by lead‐induced inhibition of the enzyme δ ‐aminolevulinic acid dehydratase. The determination of ALA in urine is based on a condensation reaction of ALA with formaldehyde and acetylacetone yielding a pyrrolizine derivate, which can be sensitively detected using fluorescence detection. 6‐Amino‐5‐oxohexanoic acid is used as an internal standard. Calibration standards are prepared in pooled urine and processed in the same way as the samples to be analysed. The method was extensively validated and the reliability data were confirmed by two independent laboratories, which have established and cross‐checked the whole procedure.

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Blei und seine Verbindungen – Bestimmung vonδ‐Aminolävulinsäure in Urin mittels HPLC‐Fluoreszenzdetektion [Biomonitoring Methods in German language, 2018]

Hartwig¹,

Arand²

2018

The MAK‐Collection for Occupational Health and Safety

View full text Add to dashboard Cite

show abstract

Lead and its compounds – Determination of δ‐aminolevulinic acid in urine by HPLC with fluorescence detection [Biomonitoring Methods, 2018]

Hartwig¹,

Arand²

2018

The MAK‐Collection for Occupational Health and Safety

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Blei und seine Verbindungen (außer Bleiarsenat, Bleichromat und Alkylbleiverbindungen) [BAT Value Documentation in German language, 2001]

Cited by 2 publications

References 44 publications

Blei und seine Verbindungen – Bestimmung vonδ‐Aminolävulinsäure in Urin mittels HPLC‐Fluoreszenzdetektion [Biomonitoring Methods in German language, 2018]

Blei und seine Verbindungen – Bestimmung vonδ‐Aminolävulinsäure in Urin mittels HPLC‐Fluoreszenzdetektion [Biomonitoring Methods in German language, 2018]

Lead and its compounds – Determination of δ‐aminolevulinic acid in urine by HPLC with fluorescence detection [Biomonitoring Methods, 2018]

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