We introduce a concept of generalized blending and deblending, develop its models and accordingly establish a method of deblended‐data reconstruction using these models. The generalized models can handle real situations by including random encoding into the generalized operators both in the space and time domain, and both at the source and receiver side. We consider an iterative optimization scheme using a closed‐loop approach with the generalized blending and deblending models, in which the former works for the forward modelling and the latter for the inverse modelling in the closed loop. We applied our method to existing real data acquired in Abu Dhabi. The results show that our method succeeded to fully reconstruct deblended data even from the fully generalized, thus quite complicated blended data. We discuss the complexity of blending properties on the deblending performance. In addition, we discuss the applicability to time‐lapse seismic monitoring as it ensures high repeatability of the surveys. Conclusively, we should acquire blended data and reconstruct deblended data without serious problems but with the benefit of blended acquisition.