Blind focusing through strongly scattering media using wavefront shaping with nonlinear feedback

Osnabrugge, Gerwin; Amitonova, Lyubov V.; Vellekoop, Ivo M.

doi:10.1364/oe.27.011673

Cited by 29 publications

(13 citation statements)

References 20 publications

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“…The only precondition is that the mask that is displayed on the SLM is appropriate and fulfills the desired task. It is by far the greatest challenge to obtain information on this phase mask, and many solutions like optical phase conjugation, ,− iterative optimization wavefront shaping, , and transmission matrix-based , approaches have been used to achieve this task. It was verified that light can be focused through approximately 100 TMFP, which corresponds to 9.6 cm tissue thickness .…”

Section: Future Perspectivesmentioning

confidence: 99%

Medical Imaging of Microrobots: Toward In Vivo Applications

et al. 2020

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Medical microrobots (MRs) have been demonstrated for a variety of non-invasive biomedical applications, such as tissue engineering, drug delivery, and assisted fertilization, among others. However, most of these demonstrations have been carried out in in vitro settings and under optical microscopy, being significantly different from the clinical practice. Thus, medical imaging techniques are required for localizing and tracking such tiny therapeutic machines when used in medical-relevant applications. This review aims at analyzing the state of the art of microrobots imaging by critically discussing the potentialities and limitations of the techniques employed in this field. Moreover, the physics and the working principle behind each analyzed imaging strategy, the spatiotemporal resolution, and the penetration depth are thoroughly discussed. The paper deals with the suitability of each imaging technique for tracking single or swarms of MRs and discusses the scenarios where contrast or imaging agent's inclusion is required, either to absorb, emit, or reflect a determined physical signal detected by an external system. Finally, the review highlights the existing challenges and perspective solutions which could be promising for future in vivo applications.

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Section: Future Perspectivesmentioning

confidence: 99%

Medical Imaging of Microrobots: Toward In Vivo Applications

et al. 2020

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“…Indeed, there are many ongoing studies that are addressing the limitations of each modality. Specifically, researchers working on deep imaging based on memory effects are combining their efforts to find ways to effectively generate a focus within a scattering medium and to extend the working range of the memory effect 140,141 . Studies are also underway to address the degradation of the TM due to the bending and twisting of multimode fibres, which will enable multimode-fibre ultrathin endoscopes to create images from curved pathways [90][91][92][93] .…”

Section: Future Perspectivesmentioning

confidence: 99%

Deep optical imaging within complex scattering media

et al. 2020

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“…Note in passing that our scheme can be realized with a similar experimental setup as shown in Refs. [49,50,51]. Nevertheless, those works mainly focusing on the enhanced intensity in the speckle pattern, whereas our work will concentrate on the reduced quantum noise of scattered modes.…”

Section: Modified Propagation Via Wavefront Shapingmentioning

confidence: 99%

Excess-noise suppression for a squeezed state propagating through random amplifying media via wave-front shaping

Li,

Sun,

Yao

2021

Preprint

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After propagating through a random amplifying medium, a squeezed state commonly shows excess noise above the shot-noise level. Since large noise can significantly reduce the signal-to-noise ratio, it is detrimental for precision measurement.To circumvent this problem, we propose a noise-reduction scheme using wavefront shaping. It is demonstrated that the average output quantum noise can be effectively suppressed even beyond the shot-noise limit. Both the decrease on amplification strength and the increase on input squeezing strength can give rise to a decrease in the suppressed average quantum noise. Our results not only show the feasibility of manipulating the output quantum noise of random amplifying media, but also indicate potential applications in quantum information processing in complex environments, such as, quantum imaging, quantum communication, and quantum key distribution.

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Blind focusing through strongly scattering media using wavefront shaping with nonlinear feedback

Cited by 29 publications

References 20 publications

Medical Imaging of Microrobots: Toward In Vivo Applications

Medical Imaging of Microrobots: Toward In Vivo Applications

Deep optical imaging within complex scattering media

Excess-noise suppression for a squeezed state propagating through random amplifying media via wave-front shaping

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