Blind No More

Berg, Tor D.; Irwin, Charles E.

doi:10.1016/j.jadohealth.2009.04.010

Journal of Adolescent Health

2009

DOI: 10.1016/j.jadohealth.2009.04.010

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Blind No More

Tor D. Berg

Charles E. Irwin

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Cited by 6 publications

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“…I note with interest the announcement (and Editorial) in the July 2009 issue of Journal of Adolescent Health indicating that ''Blind Review'' is no longer the Journal's policy [1]. More correctly, ''Double-Blind Review,'' in contrast with the time-honored policy of most peer-reviewed journals is to protect the identity of the reviewer.…”

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confidence: 98%

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Berg

Irwin

2009

Journal of Adolescent Health

Self Cite

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mentioning

confidence: 98%

“…She is correct to point out that while we have ceased the practice of double-blind review, the Journal still maintains anonymity for its reviewers [1].…”

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confidence: 99%

The Editors reply:

Berg

Irwin

2009

Journal of Adolescent Health

Self Cite

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“…( 2 , 3 , 6 ) Some journals have changed their practices due to the lack of sound empirical evidence for an effect of double-blinding on review quality. (7) Yet, a minority of journals persist in this procedure. Substance Abuse journal supports double-blinding for a number of reasons.…”

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Advancing the Peer Review Process: A Multifaceted Approach to Improving Quality

Jenkins

Gordon

2014

Substance Abuse

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A 10-year-old girl presented with a one-week history of abdominal pain, nausea and dark urine. On admission , she was icteric and drowsy with palpable liver 2 cm below the costal margin. The laboratory tests revealed elevated liver function tests with an aspartate aminotransferase level of 349 IU/L (8-40 IU/L), an alanine aminotransferase level of 1327 IU/L (7-56 IU/L), a gamma glutamyl transferase level of 370 U/L (9-24 U/L), an alkaline phosphatase level of 325 IU/L (30-100 IU/L), a total bilirubin of 3.3 mg/dL (0.2-1.2 mg/dL) and direct bilirubin of 2.2 mg/dL (0.1-0.4 mg/dL). The patient's plasma ammonia level was 67 mg/dL (15-45 mg/dL). Values of Prothrombin Time (14 seconds), activated Partial Thromboplastin Time (35 seconds) and International normalized ratio (1.12) were within normal ranges. In investigations , an immunoglobulin M (Ig M) antibody against hepatitis A virus (HAV) was positive with negative serological markers for hepatitis B and C viruses. The Widal and Weil Felix tests were negative. She was afebrile. On the 2 nd day she had generalized tonic-clonic convulsions for two times. She did not have a history of head trauma, drug intake or seizures. In physical examination there was not any flapping tremor and her ammonia level was determined as 50 mg/dL on the 2 nd day. An electroencephalogram revealed asynchronic irregular delta activity bilaterally together with sharp spike waves. Cerebrospinal fluid (CSF) analysis demonstrated mild lymphocytic pleo-cytosis (4 cells/mL), with mildly elevated proteins (85 mg/dL) and normal glucose (74 mg/dL) levels suggestive of aseptic meningitis. Evaluation under the dark-field microscope for leptospirosis was negative. She did not have a travel history and since Dengue fever or Tsutsugamushi disease are not reported in Turkey before, we did not investigate for those diseases. Magnetic resonance imaging (MRI) revealed small hyperintense areas in white matter (Fig 1). She did not have any chorea-athetotic movements reminding acute disseminated encephalomyelitis and the hyperintense areas in MRI were not large or as much as reported in acute disseminated encepha-lomyelitis. The symptoms improved with levetiracetam treatment for seizures and conservative management for HAV infection in 7 days. Follow-up brain MRI after one month revealed complete resolution. Though we did not determine the HAV IgM or RNA in CSF; since the convulsions started in the course of HAV infection with the findings of meningoen-cephalitis without any other causes and completely resolved with the treatment of this infection; these seizures were attributed to the meningoencephalitis of HAV infection. Hepatitis A virus associated meningoencephalitis in childhood is an extremely rare condition with only few cases in literature. HAV belongs to the Picor-naviridae family and other members of this family are well known to cause encephalitis; so this association is not astonishing. On the other hand, direct invasion of the central nervous system by the virus, accumulation of toxic metabolites an...

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Blind Leading the Blind?

Litt¹

2009

Journal of Adolescent Health

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Blind No More

Cited by 6 publications

References 3 publications

The Editors reply:

The Editors reply:

Advancing the Peer Review Process: A Multifaceted Approach to Improving Quality

Blind Leading the Blind?

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