Abstract. One of the outstanding problems in combinatorial design theory is concerning the existence of 2 .v; k; 1/ designs. In particular, the existence of 2 .v; k; 1/ designs admitting an interesting group of automorphisms is of great interest. Thirty years ago, a six-person team classified 2 .v; k; 1/ designs which have flag-transitive automorphism groups. Since then the effort has been to classify those 2 .v; k; 1/ designs which are block-transitive but not flagtransitive. This paper is a contribution to this program and we prove there is nonexistence of 2 .v; k; 1/ designs admitting a point-primitive block-transitive but not flag-transitive automorphism group G with socle E 8 .q/.