Blockchain was first thought of as a way to develop Bitcoin, a trustless cryptocurrency. Since then, it has moved beyond its original intent as more and more industries and interested parties see it as a method for resolving current business problems and re-stabilize mature industries. Across this study, we conduct a systematic literature review of blockchain-based applications in various sectors. The purpose of this study is to examine how blockchain has progressed over the years, its current status, what uses it has found, and how its distinctive qualities can revolutionize the way "business as usual" is done. Therefore, this review incorporates the theoretical underpinnings of a considerable number of research papers published in highly regarded scientific journals over the years, in an effort to streamline our evaluation and encompass the rapidly growing blockchain domain. We provide an extensive identification of blockchain-enabled applications covering supply chain, finance, healthcare, energy, and cloud-storage industries. This classification is premised on an organized, systematic review and conceptual data analysis of the identified publications. Additionally, we define major themes, developments, and arising areas for further research. Based on these results, we propose a number of new research avenues that will likely prove useful to scholars and professionals alike. The findings of this research suggest that the distinctive characteristics of blockchain technology, such as confidentiality, encryption, anonymity, decentralization, and authenticity, offer significant advantages to a wide range of domains and spheres of study.