“…ACAT enzymes are crucial components of cholesterol metabolism, and inhibition of their activity has great therapeutic potential, e.g., against hyperlipidemia, atherosclerosis, Alzheimer´s disease, Niemann Pick C disease, viral activity, and tumor growth [2,11,23,26,27,35,38,48,49,68,70,71]. For example, avasimibe, one of the most widely used ACAT inhibitors and a potent inducer of ACAT translocation in this study, has recently emerged as a promising anti-tumor compound [64,69,70,72].…”