Blood and Bone Marrow Transplantation for Patients with Hodgkin’s and Non-Hodgkin’s Lymphoma

Flinn, Ian W.; Berdeja, Jesús G.

doi:10.1007/978-0-387-29346-2_8

Cited by 3 publications

(3 citation statements)

References 143 publications

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“…In a review of the published data, no suggestion was found of an increased risk of prostate cancer after the administration of TBI-based regimens (17). No consensus has been reached in published studies with regard to the superiority of one conditioning regimen vs. another in the setting of ASCT for NHL (2). We recognize that other studies that have included allogeneic hematopoietic stem cell transplantation for lymphoma.…”

Section: Discussionmentioning

confidence: 84%

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Total Body Irradiation Compared With BEAM: Long-Term Outcomes of Peripheral Blood Autologous Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Liu¹,

Seftel²,

Rubinger³

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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Section: Discussionmentioning

confidence: 84%

“…This is particularly applicable to aggressive subtypes of NHL (1,2), although patients with indolent NHL might also benefit from ASCT (2,3).…”

Section: Introductionmentioning

confidence: 97%

Total Body Irradiation Compared With BEAM: Long-Term Outcomes of Peripheral Blood Autologous Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Liu¹,

Seftel²,

Rubinger³

et al. 2010

International Journal of Radiation Oncology*Biology*Physics

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“…This property has elicited excitement as to the use of these cells for therapeutic application. Indeed, HSPCs have been widely used in the clinic in recent decades for allogeneic transplantation of patients with hematologic malignancies [146,147] or genetic disorders [148][149][150][151][152]. Moreover, recent studies demonstrate that treatment of genetic disorders by transplantation of autologous bone-marrow transduced with HIV derived LV vectors is feasible and effective in animals models [153].…”

Section: Promises and Pitfalls Of Stem Cell-based Therapymentioning

confidence: 99%

Gene and cell therapy for cystic fibrosis: From bench to bedside

Conese¹,

Ascenzioni²,

Boyd³

et al. 2011

Journal of Cystic Fibrosis

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Clinical trials in cystic fibrosis (CF) patients established proof-of-principle for transfer of the wild-type cystic fibrosis transmembrane conductance regulator (CFTR) gene to airway epithelial cells. However, the limited efficacy of gene transfer vectors as well as extra- and intracellular barriers have prevented the development of a gene therapy-based treatment for CF. Here, we review the use of new viral and nonviral gene therapy vectors, as well as human artificial chromosomes, to overcome barriers to successful CFTR expression. Pre-clinical studies will surely benefit from novel animal models, such as CF pigs and ferrets. Prenatal gene therapy is a potential alternative to gene transfer to fully developed lungs. However, unresolved issues, including the possibility of adverse effects on pre- and postnatal development, the risk of initiating oncogenic or degenerative processes and germ line transmission require further investigation. Finally, we discuss the therapeutic potential of stem cells for CF lung disease.

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Linfoma mamário masculino: relato de caso

Bianco¹,

Ale²,

Neto³

et al. 2022

Revista Científica Multidisciplinar Núcleo do Conhecimento

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Linfoma mamário é uma forma rara de manifestação extra nodal do Linfoma não-Hodgkin (LNH) que tende a afetar homens na idade média de 60 anos, havendo poucos casos relatados na literatura. O diagnóstico pode se tornar difícil, devido a diferenciação necessária entre doença primária ou secundária ou manifestação extra nodal ou carcinoma mamário primário. As características mais comuns geralmente são sítios tumorais extranodais, subtipo histológico de alto grau, fenótipo B e estágio avançado. A combinação de quimioterapia, radioterapia e efeitos imunossupressores da doença de Hodgkin aumentam o risco para desenvolver LNH. A sobrevida dos pacientes com LNH agressivo está aumentando. Neste contexto, como questão norteadora, este artigo busca responder quais características radiológicas um portador de linfoma mamário tende a apresentar. Objetiva-se, portanto, relatar um caso desta doença e alertar para a possibilidade de LNH mamário, dentre as principais hipóteses diagnósticas do câncer de mama masculino. Este relato apresenta um caso clínico de um paciente com 31 anos de idade com tumor de mama. A metodologia utilizada foi a revisão de literatura junto à descrição do caso, especificando a história pessoal e familiar, além de exames subsidiários do paciente em questão. Conclui-se que diante de um paciente com nódulo mamário, o diagnóstico precoce da lesão, favorece um tratamento com altas probabilidades de cura.

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Blood and Bone Marrow Transplantation for Patients with Hodgkin’s and Non-Hodgkin’s Lymphoma

Cited by 3 publications

References 143 publications

Total Body Irradiation Compared With BEAM: Long-Term Outcomes of Peripheral Blood Autologous Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Total Body Irradiation Compared With BEAM: Long-Term Outcomes of Peripheral Blood Autologous Stem Cell Transplantation for Non-Hodgkin's Lymphoma

Gene and cell therapy for cystic fibrosis: From bench to bedside

Linfoma mamário masculino: relato de caso

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