“…Central Nervous System disorders, including Alzheimer's disease, Parkinson's disease, and Ischemic stroke, are increasingly prevalent worldwide. 1,2 While several drugs have been created to treat and manage these neurological disorders, drug delivery to the targeted site remains a significant obstacle. 3 To address drug delivery challenges and enhance medication's therapeutic effectiveness, various drug delivery systems such as polymeric microparticles, nanoparticles, and self-micro and nano-emulsifying drug delivery systems (SMEDD/SNEDD) have been developed.…”