Blood Cadmium Concentration of Residents Living near Abandoned Metal Mines in Korea

Hong, Young Seoub; Lee, Byung Kook; Park, Jung Duck; Sakong, Joon; Choi, Jae Wook; Moon, Jai Dong; Kim, Dae Seon; Kim, Byoung Gwon

doi:10.3346/jkms.2014.29.5.633

Cited by 8 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cadmium is a major environmental pollutant and a carcinogenic heavy metal ( 15 30 ), and it has been shown cadmium exposure involves diet, particularly, in children and adults not subjected to occupational exposure ( 18 ). Blood cadmium concentrations are elevated as cadmium absorption increases through divalent metal transporter 1 (DMT1) in subjects with ID or IDA ( 31 ).…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Relationships of Iron Deficiency Anemia with Blood Cadmium and Vitamin D Levels in Korean Women

Suh

Lee

et al. 2016

J Korean Med Sci

View full text Add to dashboard Cite

Anemia, iron deficiency (ID), and iron deficiency anemia (IDA) are common disorders. This study was undertaken to determine the prevalence of anemia, ID, and IDA in Korean females. We examined the associations between IDA, heavy metals in blood, vitamin D level and nutritional intakes. The study was performed using on data collected from 10,169 women (aged ≥10 yr), including 1,232 with anemia, 2,030 with ID, and 690 with IDA during the fifth Korea National Health and Nutrition Examination Survey (KNHANES V; 2010-2012). Prevalence and 95% confidence intervals were calculated, and path analysis was performed to identify a multivariate regression model incorporating IDA, heavy metals in blood, vitamin D level, and nutritional intakes. The overall prevalence of anemia, ID and IDA was 12.4%, 23.11%, and 7.7%, respectively. ID and IDA were more prevalent among adolescents (aged 15-18 yr; 36.5% for ID; 10.7% for IDA) and women aged 19-49 yr (32.7% for ID; 11.3% for IDA). The proposed path model showed that IDA was associated with an elevated cadmium level after adjusting for age and body mass index (β=0.46, P<0.001). Vitamin D levels were found to affect IDA negatively (β=-0.002, P<0.001). This study shows that the prevalence of anemia, ID, and IDA are relatively high in late adolescents and women of reproductive age. Path analysis showed that depressed vitamin D levels increase the risk of IDA, and that IDA increases cadmium concentrations in blood. Our findings indicate that systematic health surveillance systems including educational campaigns and well-balanced nutrition are needed to control anemia, ID, and IDA.

show abstract

Section: Discussionmentioning

confidence: 99%

Prevalence and Relationships of Iron Deficiency Anemia with Blood Cadmium and Vitamin D Levels in Korean Women

Suh

Lee

et al. 2016

J Korean Med Sci

View full text Add to dashboard Cite

show abstract

“…Metal mining was economically important in during the 19 th century, however, many mines were abandoned because of the change in industrial and economic conditions during the late 1970s [14]. Such abandoned metal mines have been identified as an important source of environmental heavy metal contamination and elevated levels of these toxic elements are often present in the soil and ground water of various countries [15, 16].…”

Section: Introductionmentioning

confidence: 99%

Urinary arsenic species concentration in residents living near abandoned metal mines in South Korea

Chung¹,

Kim²,

Lee³

et al. 2016

Ann of Occup and Environ Med

Self Cite

View full text Add to dashboard Cite

BackgroundArsenic is a carcinogenic heavy metal that has a species-dependent health effects and abandoned metal mines are a source of significant arsenic exposure. Therefore, the aims of this study were to analyze urinary arsenic species and their concentration in residents living near abandoned metal mines and to monitor the environmental health effects of abandoned metal mines in Korea.MethodsThis study was performed in 2014 to assess urinary arsenic excretion patterns of residents living near abandoned metal mines in South Korea. Demographic data such as gender, age, mine working history, period of residency, dietary patterns, smoking and alcohol use, and type of potable water consumed were obtaining using a questionnaire. Informed consent was also obtained from all study subjects (n = 119). Urinary arsenic species were quantified using high performance liquid chromatography (HPLC) and inductively coupled plasma mass spectrometry (ICP/MS).ResultsThe geometric mean of urinary arsenic (sum of dimethylarsinic acid, monomethylarsonic acid, As3+, and As5+) concentration was determined to be 131.98 μg/L (geometric mean; 95% CI, 116.72–149.23) while urinary inorganic arsenic (As3+ and As5+) concentration was 0.81 μg/L (95% CI, 0.53–1.23). 66.3% (n = 79) and 21.8% (n = 26) of these samples exceeded ATSDR reference values for urinary arsenic (>100 μg/L) and inorganic arsenic (>10 μg/L), respectively. Mean urinary arsenic concentrations (geometric mean, GM) were higher in women then in men, and increased with age. Of the five regions evaluated, while four regions had inorganic arsenic concentrations less than 0.40 μg/L, one region showed a significantly higher concentration (GM 15.48 μg/L; 95% CI, 7.51–31.91) which investigates further studies to identify etiological factors.ConclusionWe propose that the observed elevation in urinary arsenic concentration in residents living near abandoned metal mines may be due to environmental contamination from the abandoned metal mine.Trial registrationNot Applicable (We do not have health care intervention on human participants).

show abstract

Effects of Exposure to Lead and Cadmium on Health of Inhabitants of Abandoned Metal Mine Area in Korea

Moon

Eom

Seo

et al. 2021

Arch Environ Contam Toxicol

View full text Add to dashboard Cite

Blood Cadmium Concentration of Residents Living near Abandoned Metal Mines in Korea

Cited by 8 publications

References 15 publications

Prevalence and Relationships of Iron Deficiency Anemia with Blood Cadmium and Vitamin D Levels in Korean Women

Prevalence and Relationships of Iron Deficiency Anemia with Blood Cadmium and Vitamin D Levels in Korean Women

Urinary arsenic species concentration in residents living near abandoned metal mines in South Korea

Effects of Exposure to Lead and Cadmium on Health of Inhabitants of Abandoned Metal Mine Area in Korea

Contact Info

Product

Resources

About