Blood catecholamine-prostaglandin ratio in rats exposed and adapted to acute stress

Adaptation to physical load protects against stress and other damage. It is suggested that this protection is associated with activation of prostaglandins E (PGE) and 12 (PGI2). Plasma contents of PGE2, PGI2, and thromboxane A 2 (TxA2) and the severity of stress reaction are measured in male Wistar rats adapted to swimming. Training increases the concentrations of these prostaglandins and the prostaglandin/TxA 2 ratio, reduces almost 2-fold the severity of stress reaction as assessed by the plasma corticosterone concentration and corticosterone/insulin ratio. After stress, the PGI 2 and PGIJTxA_, in adapted rats were, respectively, 33 and 31% higher than in unadapted. These findings suggest that prostaglandins are involved in the reduction of stress reaction.

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Adaptation to physical load increases the activity of prostaglandins E and I2 and reduces stress reaction

Pshennikova

Kuznetsova

Shimkovich

et al. 1996

Bull Exp Biol Med

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Blood catecholamine-prostaglandin ratio in rats exposed and adapted to acute stress

Cited by 1 publication

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Adaptation to physical load increases the activity of prostaglandins E and I2 and reduces stress reaction

Adaptation to physical load increases the activity of prostaglandins E and I2 and reduces stress reaction

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