Blood cell-based drug delivery systems: A biomimetic platform for antibacterial therapy

Progress of cell membrane-derived biomimetic nanovesicles for cancer phototherapy

“…99 It has been shown that various nanomaterials, including polymeric nanoparticles and gold nanoparticles, can be encapsulated into nano-sized RBC membrane (RBCM)-derived vesicles to obtain prolonged blood retention and the improved permeability and retention (EPR) effect, which is a special benefit of nanoparticles in cancer research. [121][122][123] Additionally, this cell membrane encapsulation method has been shown to result in slower blood clear-ance than the PEGylated equivalents 124 and can be combined with active targeting ligands for targeted therapy. 121 Even with conventional chemical and anti-human epidermal growth factor receptor (HER) therapy, basal-like breast cancer has a depressing prognosis and a triple-negative character.…”