Blood Component Transfusion in a Tertiary Care Hospital

Sharif, Mumtaz; Saxena, Amit; Singh, Swati; Manchala, Sundeep; Jafri, Neha

doi:10.1007/s12098-020-03186-2

Cited by 7 publications

(11 citation statements)

References 12 publications

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“…A present audit showed 60.4% of all component transfusions to be appropriate and our results are consistent with the audit conducted in a tertiary care hospital in India, conducted by Bahadur et al(59.65%). 7 However similar study done by Mumtaz et al 10 showed a comparatively higher percentage of appropriate transfusions (72.6%). An audit done by Kapse et al 11 showed maximum demands of FFP and platelet concentrates are being done by the paediatric department as compared to other departments.…”

Section: Discussionmentioning

confidence: 80%

“…Many advances have been seen in the past years to encourage safe blood transfusions as non-judicious transfusions can predispose the patients to transfusion hazards and also cause wastage of health resources. 10 Hence this audit was conducted to review transfusion practices in our setup and enhance efforts in making judicious transfusions. A present audit showed 60.4% of all component transfusions to be appropriate and our results are consistent with the audit conducted in a tertiary care hospital in India, conducted by Bahadur et al(59.65%).…”

Section: Discussionmentioning

confidence: 99%

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A Clinical Audit of blood component transfusion practices in Paediatric intensive care unit of a Tertiary Care Hospital, Rawalpindi

Zafar¹,

Sarosh

Tariq

et al. 2022

JRMC

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Background: To audit the practices involved in blood component transfusion in the management of patients in paediatric intensive care unit of our hospital and to determine the appropriateness of transfusion after comparing them with clinical practice guidelines recommended by Royal Children Hospital (RCH). Methods: All patients admitted in pediatric intensive care which were managed with blood component transfusions were retrospectively audited for 8 weeks. Management details including indications of transfusion and its appropriateness were recorded. Clinical practice guidelines recommended by Royal Children Hospital (RCH) were used as standards. Results: One hundred and ninety-two transfusions were done during the study period out of which 58 percent were done to males and 41 percent to females. Majority of transfusions were done in infants (44%) and O Positive blood group was found rampant among blood groups of all recipients (33.3%). Red cell concentrates were predominantly (55.7%) and appropriately (72%) transfusion among all blood components. Platelet concentrates were most inappropriately transfused (57%) followed by fresh frozen plasma (54%) and red cell concentrates (27%). There was significant percentage of inappropriate transfusion of all blood components (p=0.00). Conclusion: All blood components were significantly found inappropriately transfused, commonest component being platelet concentrates.

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Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 99%

A Clinical Audit of blood component transfusion practices in Paediatric intensive care unit of a Tertiary Care Hospital, Rawalpindi

Zafar¹,

Sarosh

Tariq

et al. 2022

JRMC

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“…2, 3 The decision to transfuse is crucial because there are various complications associated with it which include transfusion transmitted diseases, ABO incompatibility, alloimmunization, bacterial contamination, gut ischemia, transfusion related acute lung injury (TRALI) and other immunomodulation phenomena. 1,[3][4][5] Various guidelines have been devised to guide transfusion practices and to outline indications of transfusions so that complications are avoided. 2,6,7 Despite these guidelines and known complications of transfusion, there have been reports of unnecessary and inappropriate blood product transfusions i.e., transfusing blood components in absence of recommended indications.…”

Section: Introductionmentioning

confidence: 99%

“…2,6,7 Despite these guidelines and known complications of transfusion, there have been reports of unnecessary and inappropriate blood product transfusions i.e., transfusing blood components in absence of recommended indications. 1,2,4,8 To our knowledge and literature search, there has been only a single study done in Pakistan to evaluate appropriateness of blood product transfusions in critically ill children in Rawalpindi, which showed significantly high percentages of inappropriate blood component transfusions. 8 This data is important to reflect our current transfusion practices and to highlight areas of improvement, teaching and training.…”

Section: Introductionmentioning

confidence: 99%

Blood product transfusion practices in pediatric critically ill patients at a tertiary care hospital, Pakistan

et al. 2023

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Objective: To determine the frequency of inappropriate blood product transfusions in pediatric critically ill patients. Methods: We collected data for this descriptive study from January to December 2020 at the Pediatric Intensive Care Unit (PICU) of Dr. RKMP Civil Hospital, Karachi. We included all patients one month to 12 years of age, admitted to pediatric intensive care unit and received any blood product transfusion. We reviewed their medical records and noted the demographic and clinical variables, type of blood product transfused with its indication and determined whether transfusion was appropriate or not, as per the standard guidelines and consensus recommendations. Results: Number of patients who were transfused was n=39, out of which females were 51.3%. Mean age of the patients was 49.0 months ±50.9 months. Total number of transfusions done were n=135, with most common blood product transfused being Fresh Frozen plasma (FFP) in 44.4%. A total of n=117 (86.66%) transfusion were appropriate as per the standard guidelines, while 18 (13.33%) were inappropriate (P-value <0.5). The most common indication of FFP transfusion was INR>2.0 in 51.6%, for Packed red cell transfusion was hemoglobin between 5 and 7 gm/dl in 35.5% and for Platelets was <20,000 with risk of bleeding in 36.6%. Conclusion: This study highlights the occurrence of inappropriate transfusions in critically ill pediatric patients. We need to reinforce the knowledge of our health care workers and display the guidelines in intensive care units. doi: https://doi.org/10.12669/pjms.39.4.7503 How to cite this: Rafique M, Nasir S, Kamran A, Jamal A. Blood product transfusion practices in pediatric critically ill patients at a tertiary care hospital, Pakistan. Pak J Med Sci. 2023;39(4):---------. doi: https://doi.org/10.12669/pjms.39.4.7503 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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“…In both developed and developing countries, inappropriate prescription of blood components occurs in up to 36% of cases 2 . The rational prescription of transfusion therapies is essential due to limited resources and growing demand 3 .…”

Section: Introductionmentioning

confidence: 99%