Blood counts in extremely low birthweight infants.

McIntosh, Neil; Kempson, C; Tyler, Robert

doi:10.1136/adc.63.1.74

Cited by 27 publications

(5 citation statements)

References 5 publications

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“…Contrary to the increased proportion of neutrophilic granulocytes, steroids often induce eosinopenia and lymphopenia (2). In neonates the haematologic reaction on steroids has not been extensively investigated: some case reports suggest an identical reaction as found in older children and adults (7,8), whereas others report no changes at all in neonatal haematologic parameters after steroids (5). Our study shows in both very preterm infants as well as in more mature babies that glucocorticosteroids cause a significant increase in WBC-count with an increased number of neutrophilic granu- locytes, whereas the number of eosinophils decreased.…”

Section: So) Values Of Wbc-and Platelet Counts (X109jl) and The Diffementioning

confidence: 47%

The Effect of Glucocorticosteroids on the Neonatal Blood Count

Winter

Bel

1991

Acta Paediatrica

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To investigate the influence of glucocorticosteroid therapy on the neonatal blood count, the haematologic data of 68 preterm and term infants, who had received a single dose of 1 mg dexamethasone i.v., were reviewed. White blood cell (WBC) count and platelet count increased after steroid therapy. The increase in WBCs was associated with an increase in the number of neutrophilic granulocytes, whereas the number of eosinophils decreased. We conclude that glucocorticosteroids after the neonatal blood count and influence its value as a diagnostic marker for bacterial infections.

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Section: So) Values Of Wbc-and Platelet Counts (X109jl) and The Diffementioning

confidence: 47%

The Effect of Glucocorticosteroids on the Neonatal Blood Count

Winter

Bel

1991

Acta Paediatrica

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“…Following the publication of CBC reference values by Xanthou (7) and Manroe et al (8), several authors have reported a higher incidence of neutropenia in VLBW infants compared with term infants (4,(9)(10)(11)(12)(13)(14). The incidence of neutropenia (the lower ANC reference range was set between 1000 and 2000 mm ¡3 ) was higher in preterm infants (13% in infants weighing < 2500 g, or up to 58% in infants with birthweight < 2000 g, or 55% in VLBW infants with intraventricular hemorrhage) compared with 3% in term infants.…”

Section: Discussionmentioning

confidence: 99%

Late-onset neutropenia in very low birthweight infants

Chirico¹,

Motta²,

Villani³

et al. 2002

Acta Paediatrica

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“…The total and differential leucocyte counts in healthy children has been well studied in neonates ( McIntosh, Kempson & Tyler 1988; Mouzinho et al 1994 ; Schelonka et al 1994 ) and children of school age ( Taylor et al 1997 ). In contrast, values for children between these ages appear to be drawn mainly from the work of Allbritton (1952) who produced smoothed data from reports published over the first half of the twentieth century.…”

Section: Discussionmentioning

confidence: 99%

“…The total and di¡erential leucocyte counts in healthy children has been well studied in neonates (McIntosh, Kempson & Tyler 1988;Mouzinho et al 1994;Schelonka et al 1994) and children of school age (Taylor et al 1997).…”

Section: Discussionmentioning

confidence: 99%

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

Bellamy¹,

Hinchliffe²,

Crawshaw³

et al. 2000

Clinical &Amp; Laboratory Haematology

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Reference ranges for the total and differential leucocyte counts were determined from venous blood collected at 2, 5 and 13 months of age from a cohort of 112 healthy children of north European ancestry. At 2, 5 and 13 months, the ranges for neutrophils were found to be 0.7-4.7, 1.1-5.6 and 1.0-7.6 x 109/l, and for lymphocytes 3.3-10.5, 3.4-11.3 and 3.5-10.4 x 109/l, respectively. The upper limits for monocytes at each age were 1.2, 1.2 and 0.91 x 109/l, and for eosinophils 0.84, 1.0 and 0.88 x 109/l, respectively. Mean counts for all cell types, except monocytes, increased between 2 and 5 months of age. There was little change in mean counts between 5 and 13 months. Statistically significant correlations existed between the numbers of each cell type at 2 months of age, and were still present at 13 months between monocytes and each of the granulocyte series and between basophils and all other cell types. By comparison with older data these findings indicate a lower reference limit for neutrophils at 2 months of age, and a narrower range for this cell type at both 2 and 5 months of age. Reference ranges for lymphocytes and eosinophils are wider than indicated by some previous studies.

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Blood counts in extremely low birthweight infants.

Cited by 27 publications

References 5 publications

The Effect of Glucocorticosteroids on the Neonatal Blood Count

The Effect of Glucocorticosteroids on the Neonatal Blood Count

Late-onset neutropenia in very low birthweight infants

Total and differential leucocyte counts in infants at 2, 5 and 13 months of age

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