Blood Culture and Pleural Fluid Culture Yields in Pediatric Empyema Patients

Stankey, Christina T; Spaulding, Alicen B; Doucette, Angela; Hamre, Karen E. S.; Wheeler, William E.; Pomputius, William F.; Kurachek, Stephen C.

doi:10.1097/inf.0000000000001940

Cited by 33 publications

(35 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In contrast to the overall decrease in PPE/PE associated with S. pneumoniae, we observed an increase in the incidence and proportion of PPE/PE associated with S. pyogenes, reaching a maximum in 2015/16 when S. pyogenes accounted for 34% of all bacteria detected. A worldwide increase in invasive infection by S. pyogenes has been noted since the 1980s [38], but only one recent study has reported a similar proportional increase in PPE/PE associated with S. pyogenes [39]. However, natural fluctuations of S. pneumoniae serotypes and S. pyogenes may also have an impact on the observed pattern.…”

Section: Discussionmentioning

confidence: 97%

“…Although we offered eubacterial PPCR to all hospitals free of charge, physicians did not make use of this option in all cases. In addition, pre-hospitalization antibiotic treatment in about 30% of children probably resulted in lower rates of detection of bacteria [39]. Furthermore, the exploratory trend analyses must be interpreted with caution because of the small numbers of observations per SY.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010–2017: a nationwide surveillance study

Liese

Schoen

Linden

et al. 2019

Clinical Microbiology and Infection

View full text Add to dashboard Cite

a b s t r a c tObjectives: Parapneumonic pleural effusions/empyema (PPE/PE) are severe complications of communityacquired pneumonia. We investigated the bacterial aetiology and incidence of paediatric PPE/PE in Germany after the introduction of universal pneumococcal conjugate vaccine (PCV) immunization for infants. Methods: Children <18 years of age hospitalized with pneumonia-associated PPE/PE necessitating pleural drainage or persisting >7 days were reported to the German Surveillance Unit for Rare Diseases in Childhood between October 2010 and June 2017. All bacteria detected in blood or pleural fluid (by culture/PCR) were included, with serotyping for Streptococcus pneumoniae. Results: The median age of all 1447 PPE/PE patients was 5 years (interquartile range 3e10). In 488 of the 1447 children with PPE/PE (34%), 541 bacteria (>40 species) were detected. Aerobic gram-positive cocci accounted for 469 of 541 bacteria detected (87%); these were most frequently Streptococcus pneumoniae (41%), Streptococcus pyogenes (19%) and Staphylococcus aureus (6%). Serotype 3 accounted for 45% of 78 serotyped S. pneumoniae strains. Annual PPE/PE incidence varied between 14 (95%CI 12e16) and 18 (95%CI 16e21) PPE/PE per million children. Incidence of S. pneumoniae PPE/PE decreased from 3.5 (95%CI 2.5e4.6) per million children in 2010/11 to 1.5 (95%CI 0.9e2.4) in 2013/14 (p 0.002), followed by a reincrease to 2.2 (95%CI 1.5e3.2) by 2016/17 (p 0.205). Conclusions: In the era of widespread PCV immunization, cases of paediatric PPE/PE were still caused mainly by S. pneumoniae and, increasingly, by S. pyogenes. The re-increase in the incidence of PPE/PE overall and in S. pneumoniae-associated PPE/PE indicates ongoing changes in the bacterial aetiology and requires further surveillance.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010–2017: a nationwide surveillance study

Liese

Schoen

Linden

et al. 2019

Clinical Microbiology and Infection

View full text Add to dashboard Cite

show abstract

“…The possibility of a fungal wound infection should also be included in this differential diagnosis. For chronic wound infections, the literature consistently recommends obtaining fungal cultures to isolate the agent [9, 11, 12] because fungal culture is known to have higher sensitivity than fungal microscopy [13, 14]. To our knowledge, Trichophyton has not been reported as a primary pathogen in surgical wound infections.…”

Section: Discussionmentioning

confidence: 99%

Trichophytonas a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy

Gaffar

Birknes

Cunnion

2018

Case Reports in Pediatrics

View full text Add to dashboard Cite

Fungal infections are rare causes of acute surgical wound infections, but Candida is not an infrequent etiology in chronic wound infections. Trichophyton species is a common cause of tinea capitis but has not been reported as a cause of neurosurgical wound infection. We report a case of Trichophyton tonsurans causing a nonhealing surgical wound infection in a 14-year-old male after hemicraniectomy. His wound infection was notable for production of purulent exudate from the wound and lack of clinical improvement despite empiric treatment with multiple broad-spectrum antibiotics targeting typical bacterial causes of wound infection. Multiple wound cultures consistently grew Trichophyton fungus, and his wound infection clinically improved rapidly after starting terbinafine and discontinuing antibiotics.

show abstract

“…Antimikrobiyal tedavide sağlanan gelişmeler sonrasında PA'da etken mikroorganizmaların saptanma oranlarında dramatik düşüşler gözlenmiştir. Stankey ve arkadaşları bu oranın %60'dan %30'a düştüğünü belirtmiştir [11] . Ülkemizde ise Ertuğrul ve arkadaşları kendi serilerinde %24.7 hastada plevral mayi kültüründe üreme sağlamışlardır [12] .…”

Section: Bulgularunclassified

“…Etkili plevral drenaj, uygun antibiyoterapi, gereğinde cilt/cilt altı dokulara yönelik debridman/drenaj ve hastanın genel durumunun desteklenmesi tedavinin temelleridir. Tuzaklanmış akciğerin serbestlenmesi ve ekspansasyon sağlanması, medikal tedavinin etkisiz kaldığı loküle plevral odakların ortadan kaldırılması majör cerrahi için endikasyonlardır [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] . Serimizde AN hastaları genel ampiyem popülasyonuna göre daha geç opere edilmişti.…”

Section: Bulgularunclassified

An Overlooked Complication, Empyema Necessitatis: An Analysis of 766 Empyema Cases

Avcı¹,

Kuşçu²,

Ulu³

et al. 2019

FLORA

View full text Add to dashboard Cite

Giriş: Plevral ampiyem (PA), plevra yaprakları arasında infekte mayi bulunmasıdır. Ampiyema nesessitatis (AN) ise PA'nın pariyetal plevra ve endotorasik fasiayı geçerek çevre yumuşak dokular içinde yayılması ve cilt altı yayılımı ile bazen cilde fistülize olmasıyla karakterize, nadir bir komplikasyonudur. Ayırıcı tanıda karmaşıklığa neden olur. Bu çalışmada, AN risk faktörlerinin tespit edilmesi, tanı ve tedavisinde tecrübelerimizin paylaşımı amaçlanmıştır.

show abstract

Blood Culture and Pleural Fluid Culture Yields in Pediatric Empyema Patients

Cited by 33 publications

References 9 publications

Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010–2017: a nationwide surveillance study

Changes in the incidence and bacterial aetiology of paediatric parapneumonic pleural effusions/empyema in Germany, 2010–2017: a nationwide surveillance study

Trichophytonas a Rare Cause of Postoperative Wound Infection Resistant to Standard Empiric Antimicrobial Therapy

An Overlooked Complication, Empyema Necessitatis: An Analysis of 766 Empyema Cases

Contact Info

Product

Resources

About