Blood Donation and Collection

Zeger, Gary; Selogie, Eileen; Shulman, Ira A.

doi:10.1016/b978-0-443-06981-9.50016-8

Cited by 7 publications

(7 citation statements)

References 102 publications

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“…In the United States and many other economically developed nations, all of the blood is given by volunteer and nonremunerated donors. Donated whole blood is then made into transfusable components, which include, but are not limited to, packed red blood cells (RBCs), platelets and frozen plasma or cryoprecipitate (Zeger et al, 2007). Therefore, in this paper, we focused on the queue theory to minimize the total cost of the chain and we achieve two other goals that are minimizing the waiting time for customers and minimizing the establishment time for mobile blood centers.…”

Section: Placement-assignmentmentioning

confidence: 99%

Mathematical modeling for optimizing the blood supply chain network

Dehaghani

Nawaz

Sultanie

et al. 2021

MSCRA

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PurposeThis research studies a location-allocation problem considering the m/m/m/k queue model in the blood supply chain network. This supply chain includes three levels of suppliers or donors, main blood centers (laboratories for separation, storage and distribution centers) and demand centers (hospitals and private clinics). Moreover, the proposed model is a multi-objective model including minimizing the total cost of the blood supply chain (the cost of unmet demand and inventory spoilage, the cost of transport between collection centers and the main centers of blood), minimizing the waiting time of donors in blood donating mobile centers, and minimizing the establishment of mobile centers in potential places.Design/methodology/approachSince the problem is multi-objective and NP-Hard, the heuristic algorithm NSGA-II is proposed for Pareto solutions and then the estimation of the parameters of the algorithm is described using the design of experiments. According to the review of the previous research, there are a few pieces of research in the blood supply chain in the field of design queue models and there were few works that tried to use these concepts for designing the blood supply chain networks. Also, in former research, the uncertainty in the number of donors, and also the importance of blood donors has not been considered.FindingsA novel mathematical model guided by the theory of linear programming has been proposed that can help health-care administrators in optimizing the blood supply chain networks.Originality/valueBy building upon solid literature and theory, the current study proposes a novel model for improving the supply chain of blood.

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Section: Placement-assignmentmentioning

confidence: 99%

Mathematical modeling for optimizing the blood supply chain network

Dehaghani

Nawaz

Sultanie

et al. 2021

MSCRA

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“…[1] A low blood donation rate can lead to shortages of blood and blood products, which can have serious consequences for patients in need and it can result in delayed or cancelled medical procedures, and compromise patient care. [2] The World Health Organization (WHO) recommends screening donated blood for infections in accordance with quality system requirements. Screening for HIV, hepatitis B, hepatitis C, and syphilis is obligatory to maintain the safety of the blood supply.…”

Section: Introductionmentioning

confidence: 99%

“…[4] Nonetheless, data reported to the WHO indicates an increase in voluntary unpaid blood donations in LMIC, signifying positive progress in addressing this critical issue. [2] A review article published in 2019 showed a significant difference in blood donation motivation across 5 geographical regions with similar economic profiles. The predictive factor for blood donation was identified as behavioral intention.…”

Section: Introductionmentioning

confidence: 99%

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Knowledge, attitude, and practice of blood donation among undergraduate medical students in Syria

Salem,

Kahwaji,

Owais

et al. 2024

Medicine

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Timely transfusion of blood products is crucial, particularly in critical medical situations. Inadequate blood donation rates pose a significant threat to public health, potentially compromising patient care. This study aims to investigate the attitudes and willingness of Syrian college students to engage in blood donation, assess the prevalence of voluntary blood donation, evaluate their understanding of the determinants and procedures involved in the donation process, and identify the key factors influencing their behavior. A cross-sectional study was conducted employing a self-administered questionnaire, distributed in both electronic and hard copy formats among college students. Data analysis was performed using the R Statistical Software. Results were presented in terms of odds ratios (OR), with statistical significance defined at a P value of .05 and a 95% confidence interval. A total of 673 medical students participated in this study, with an average age of 21.6 years. The majority (59.2%) reported a good economic status, and a high level of knowledge (99.7%). A substantial proportion (40.4%) agreed with the notion that blood donation constitutes a personal duty for every eligible individual. Multiple comparison tests revealed a statistically significant P value of .0009716, specifically concerning individuals with low economic status. Our study demonstrates a positive attitude among college students towards voluntary blood product donation. However, the majority have not engaged in voluntary activities unless mandated for specific certification purposes. Donation rates were relatively higher than the reported rates in other similar studies conducted in Middle Eastern countries.

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“…3 Whole blood collections do not require collection instrument purchase; however, whole blood donations only yield 1 unit of CP (vs up to 4 units per collection by apheresis) and whole blood donors cannot donate more often than every 8 weeks (vs every 4 weeks or less for plasma donors). 4 On the other hand, venous access issues are more common, the cost is higher, and the collection time is longer for apheresis collections. 5 Collection of plasma by apheresis can be performed either as part of an apheresis platelet collection as concurrent plasma, or as a stand-alone plasma collection procedure.…”

Section: Introductionmentioning

confidence: 99%

Rapidly Establishing a Hospital-Based Convalescent Plasma Collection Center With the Alyx Apheresis Collection Device

et al. 2021

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The effort to collect convalescent plasma from individuals who recovered from COVID-19 began in earnest during the spring of 2020. Either whole blood or apheresis donations were obtained, the latter yielding higher numbers of units per donor per collection and more frequent collections. The NorthShore University HealthSystem blood donor center purchased 2 Alyx (Fresenius Kabi) apheresis plasma collection devices and quickly implemented them in order to collect COVID-19 convalescent plasma. Apheresis-experienced and inexperienced phlebotomists operated the instruments. Donors were collected >14 days from symptom resolution and all donors were negative by SARS-CoV-2 nasopharyngeal swab. Both internal metrics of performance as well as a post donation survey were used to evaluate the feasibility implementing this collection program. During the first 100 days of the collection program, 650 plasma units were collected. In particular, during the first week of the program, 38 units were collected and distributed to hospitals under the emergency investigational new drug and expanded access program. Fifty-one donors (15%) were deferred due to vital signs out of range or donor screening questions. Thirty-one donors (10%) were deferred due to positive nasopharyngeal swab. Lower than target yield occurred in 16.6% of collections due to donor reactions or flow errors. Donors rated the overall program lower, but not the staff, when they reported symptoms related to collection. In conclusion, a hospital-based apheresis convalescent plasma collection program can be rapidly implemented. Donor reaction rates and vein infiltration rates should be carefully monitored for each phlebotomist.

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Blood Donation and Collection

Cited by 7 publications

References 102 publications

Mathematical modeling for optimizing the blood supply chain network

Mathematical modeling for optimizing the blood supply chain network

Knowledge, attitude, and practice of blood donation among undergraduate medical students in Syria

Rapidly Establishing a Hospital-Based Convalescent Plasma Collection Center With the Alyx Apheresis Collection Device

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