Blood flow analysis inside different arteries using non-Newtonian Sisko model for application in biomedical engineering

Toghraie, Davood; Esfahani, Navid Nasajpour; Zarringhalam, Majid; Shirani, Nima; Rostami, Sara

doi:10.1016/j.cmpb.2020.105338

Cited by 53 publications

(14 citation statements)

References 22 publications

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“…Therefore, the total number of grid nodes for each case in this study is chosen to be approximately 2.41 million. Computational fluid dynamics solves blood flow eqs 1-3 discretely at each grid node using the algorithm of the semi-implicit method for pressure linked equations (SIMPLE) (Toghraie et al, 2020) in the software FLUENT (ANSYS, Inc., Canonsburg, PA, United States). The simulation process of each case was performed in ten parallel threads on a computer server (Intel i7-8700K 3.70GHz CPU), and each case finished in nearly 2 days by setting the convergent residuals for both the pressure and momentum as 10 −6 .…”

Section: Grid Refinement Studymentioning

confidence: 99%

Hemodynamic Analysis of VenaTech Convertible Vena Cava Filter Using Computational Fluid Dynamics

Wang

Huang

Zhou

et al. 2020

Front. Bioeng. Biotechnol.

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The VenaTech convertible filter (VTCF) has been widely used as an inferior vena cava (IVC) filter to prevent fatal pulmonary embolism in patients. However, its hemodynamics that greatly affect the filter efficacy and IVC patency are still unclear. This paper uses computational fluid dynamics with the Carreau model to simulate the non-Newtonian blood flows around the VTCF respectively deployed in the normal, reverse and three converted states in an IVC model. The results show that the prothrombotic stagnation zones are observed downstream from the normal, reverse and small open VTCFs, with the streamwise length is nearly eight times the IVC diameter. The no-slip boundary conditions of the thin-wire VTCF arms lead to the "viscous block" effect. The viscous block accelerates the blood flow by 5-15% inside the IVC and enhances the filter wall shear stress up to nearly 20 times that of the IVC only, which contributes to clot capture and thrombus lysis. The relative flow resistance is defined to evaluate the filter-induced resistance on the IVC blood flow that can be regarded as an index of IVC patency with the filter deployment. The flow resistance of the normal VTCF deployment increases dramatically by more than 60% compared with that of the IVC only and is a little higher (6%) than that of the reverse case. As the VTCF converts to a fully open configuration, the flow resistance gradually decreases to that of no filter. This work shows that even very thin VTCF arms can result in the viscous block effect and may cause significant hemodynamic impacts on clot capture, potential thrombosis and flow impedance inside the IVC. The present study also shows that CFD is a valuable and feasible in silico tool for analyzing the IVC filter hemodynamics to complement in vivo clinical and in vitro experimental studies.

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Section: Grid Refinement Studymentioning

confidence: 99%

Hemodynamic Analysis of VenaTech Convertible Vena Cava Filter Using Computational Fluid Dynamics

Wang

Huang

Zhou

et al. 2020

Front. Bioeng. Biotechnol.

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“…The COVID-19 virus causes inflammation throughout the human body and is causing many patients to die due to acute respiratory distress syndrome (ARDS) (for details visit sciencemag.org). Toghraie et al [13] recently simulated the blood flow in arteries using Sisko fluid model. The authors pointed out that medical doctors require help from others including CFD specialists to understand further the complex blood circulation system and possible clinical therapeutic measures to cure from different diseases.…”

Section: Introductionmentioning

confidence: 99%

“…The applied force will act against the flow, enabling us to control the flow's current whenever required. As pointed out in [13], human blood flowing in arteries can be modelled by Sisko fluid and the shape of the arteries is cylindrical in nature, which contract and swell according to blood temperature and body requirements. Thus stretching/shrinking phenomena coupled with curvature of the flowing channel are important concepts in understanding such flow behaviors.…”

Section: Introductionmentioning

confidence: 99%

Combined Effects of Binary Chemical Reaction/Activation Energy on the Flow of Sisko Fluid over a Curved Surface

et al. 2021

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In this study, a modified Sisko fluid with Buongiorno model effects over a curved surface was considered. The MHD was applied normally to the flow direction, and the effects of chemical reacted and active energy at the curved surface is also discussed. We chose this pertinent non-Newtonian fluid model since it best represents blood composition, and thus helps us venture into complex blood flow problems. Since the flow is discharged over a curved shape, we therefore commissioned curvilinear coordinates to best portray our envisaged problem. We were also required to define various sundry parameters to make our mathematical equations easily solvable. Mathematical modelling was completed by considering traditional assumptions, including boundary layer approximation. Numerical simulation was conducted using MATLAB solver bvp4c. Several numerical tests were conducted to select the best blend of the linked parameters. We noticed thermal flux upsurged when the chemical reaction parameter was increased with the magnetic indicator parameter caused the flow to slow down, while an increasing amount of activation energy enhanced the concentration of the fluid. The numerical results and impacts of assorted parameters on different profiles are elaborated with the help of graphs and a table.

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“…Nabil and Mostapha [6] investigated the Hall current and Joule heating effects of a peristaltic flow of a Sisko fluid with moderate stenosis via a porous medium in the tapered artery with slip and convective process parameters. Toghraie et al [7] analyzed blood flow within various arteries using a non-Newtonian Sisko model for use in bioengineering. Agoor et al [8] investigated peristaltic flow with heat transfer to a Sisko fluid in ciliated arteries.…”

Section: Introductionmentioning

confidence: 99%

Three-Dimensional Radiative Bioconvective Flow of a Sisko Nanofluid with Motile Microorganisms

et al. 2021

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The progressive and enhanced thermal mechanisms of nanoparticles has motivated researchers to give attention to this topic in recent years. The synthesizing and versatile applications of such materials include cooling and heating controlling processes, solar systems, energy production, nanoelectronics, hybrid-powered motors, cancer treatments, and renewable energy systems. Moreover, the bioconvection of nanofluids allows for some motivating applications in this era of bioengineering and biotechnology, such as biofuels, biosensors, and enzymes. With these interesting motivations and applications, this study elucidated upon the three-dimensional bioconvection flow of a Sisko fluid (base fluid) in the presence of a nanofluid over a stretched surface. The additional thermal features of radiation were also incorporated to modify the analysis. The rheological features of shear thinning and shear thickening that are associated with the Sisko nanofluid were comprehensively studied. The problem was formulated using highly nonlinear and coupled differential equations, which were numerically simulated via a shooting scheme. The salient physical applications of flow parameters were graphically underlined in view of shear-thinning and shear-thickening scenarios. The results showed that a decrease in velocity in the presence of buoyancy ratio forces was more conducive to the shear-thinning phenomenon. The increase in temperature profile due the thermal Biot number and surface heating source parameter seemed to be more inflated in the shear-thinning scenario. A lower motile microorganism profile was noted for the bioconvection Lewis number.

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Blood flow analysis inside different arteries using non-Newtonian Sisko model for application in biomedical engineering

Cited by 53 publications

References 22 publications

Hemodynamic Analysis of VenaTech Convertible Vena Cava Filter Using Computational Fluid Dynamics

Hemodynamic Analysis of VenaTech Convertible Vena Cava Filter Using Computational Fluid Dynamics

Combined Effects of Binary Chemical Reaction/Activation Energy on the Flow of Sisko Fluid over a Curved Surface

Three-Dimensional Radiative Bioconvective Flow of a Sisko Nanofluid with Motile Microorganisms

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