Blood flow rate during orthostatic pressure changes in the pulp skin of the first toe

Abstract

The microvascular responses to changes of orthostatic blood pressure differed among the three groups (normal subjects, patients with intermittent claudication, patients with critical chronic leg ischaemia). The heat washout method may be used to detect the functional significance of occlusive atherosclerotic disease.

Integrity of venoarteriolar reflex determines level of microvascular skin flow enhancement with intermittent pneumatic compression

“…17,18 Our data is in accordance with previous studies demonstrating an impaired VAR in patients with intermittent claudication due to PAD. 9,17,19 In keeping with previous reports, we also found lower levels of skin blood flow augmentation with IPC in patients with PAD than in healthy controls. 1,4,[20][21][22] Different physiologic mechanisms through which IPC induces its flow augmentation effects have been proposed.…”

Heat‐washout – an objective method for diagnosing neuropathy and atherosclerosis in diabetic patients

“…The increase exceeded 50% in 5 of 7 of these subjects. This phenomenon was not seen in healthy subjects, where the BFR increased in only four of six and in no subjects more than 20% (Midttun et al ., ). In the diabetic patients in the present study, the measured BFR in the 1st toe increased when the leg was lowered 50 cm below heart level in seven of nine.…”

“…The heat‐washout method is a non‐invasive method for measuring BFR in ml (100 g · min) −1 in the 2–3 mm superficial layer of the skin. The method was introduced in 1996 by Midttun, Sejrsen and Colding‐Jørgensen and has among others been proven useful for measuring skin BFR in fingers and toes (Midttun & Sejrsen, ; Midttun et al ., , , , ) (Fig. ).…”

Heat‐washout measurements compared to distal blood pressure and perfusion in orthopaedic patients with foot ulcers

“…The method was introduced in by Midttun et al . and has among others been proven useful for measuring skin BFR in fingers and toes in patients with and without atherosclerosis and diabetes (Midttun et al ., , , , ).…”