Microvascular free tissue transfer is essential in complex head and neck reconstruction. The mainstay of microvascular anastomosis has classically been the suture technique, but the coupling device has emerged as a valuable alternative. Couplers are commonly used for venous anastomoses, but most head and neck reconstructive surgeons do not routinely couple arteries. However, coupling may afford reconstructive surgeons a unique tool for addressing difficult arterial anastomoses. In this case report, we describe the successful use of a microvascular coupler for salvage arterial anastomosis after recurrent thrombosis following multiple attempts at suture anastomosis in head and neck free flap reconstruction.