Blood Group Change in Pediatric Leukemia: A Rare Phenomena

Radhakrishnan, Venkatraman; Mishra, Sourav; Bhaskar, Narmada; Sagar, Tenali Gnana

doi:10.1007/s12098-015-2019-5

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…The original patient's blood group was confirmed to be B. The study of Radhakrishnan et al (2016) involved an AML patient who was (O+) at the time of presentation [ 63 ]. His disease was in remission after two sessions of induction chemotherapy, but his blood type changed to (A+).…”

Section: Reviewmentioning

confidence: 99%

Association of Leukemia With ABO Blood Group Distribution and Discrepancy: A Review Article

Elzein

2024

Cureus

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The ABO system is an essential blood group in clinical transfusion medicine implicated in several human diseases. The ABO system has been investigated for over a century, with various studies exploring potential links to disease susceptibility. The study examines the possible relationship between leukemia and the distribution and the ABO blood group system discrepancy. A comprehensive review was conducted on the recommended databases to review the ABO blood groups, their association with leukemia, and the expected changes in blood groups among leukemia patients. The study highlights different kinds of leukemia, such as acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML), and chronic lymphocytic leukemia (CLL), their characteristics, and their relationship with ABO blood groups. The document concludes that studying ABO blood group distributions among leukemia patients showed that the most common blood group in acute leukemia is the A group, while in chronic leukemia, the O group is predominant; more studies are required. This study also confirmed an association between leukemia and ABO blood group discrepancy.

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Section: Reviewmentioning

confidence: 99%

Association of Leukemia With ABO Blood Group Distribution and Discrepancy: A Review Article

Elzein

2024

Cureus

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“…In a report by Radhakrishnan et al ( 9 ), the authors presented two leukemic patients with blood group change during their treatment. The mechanism by which the blood group changed in leukemic patients was not clearly described, but they hypothesized that through epigenetic modifications on the transcription regulating regions of ABO gene in RBCs, malignant cells inhibit the transcription antigens, consequently altering the blood group.…”

Section: Dear Editor-in-chiefmentioning

confidence: 99%