2020
DOI: 10.1111/trf.15981
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Blood group‐related antigen Ley on human platelets and its involvement in platelet aggregation via a possible interaction with CD61

Abstract: Background The Ley antigen is a carbohydrate chain belonging to the ABH‐Lewis blood group family. Ley has been reported to be present on red blood cells (RBCs) and granulocytes, but its distribution and function in platelets remain unknown. There are a variety of glycoproteins on platelets, which may carry the Ley antigen. This study aims to investigate the expression pattern and the function of Ley in human platelets. Study design and methods Flow cytometry, Western blot, and immunofluorescence assays were pe… Show more

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