Blood levels of cadmium and lead in residents near abandoned metal mine areas in Korea

Park, Dong-Uk; Kim, Dae Seon; Yu, Seung Do; Lee, Kyeong Min; Ryu, Seung-Hun; Kim, Soo Geun; Yang, Won Ho; Park, Doo Yong; Hong, Yeong Seoub; Park, Jung Duck; Lee, Byung Kook; Moon, Jai Dong; Sakong, Joon; Ahn, Seung Chul; Ryu, Jung Min; Jung, Soon‐Won

doi:10.1007/s10661-014-3770-1

Cited by 21 publications

(11 citation statements)

References 14 publications

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“…Moreover, there were significant correlations between the concentrations of some elements in different tissues; for instance, the contents of Se, As, Cr and Ni in hair were significantly positively correlated to those in blood. For Cd, an insignificant correlation was found between hair and blood concentrations, which suggested that hair Cd concentration is relatively independent of the Cd level in the blood, in agreement with earlier studies in cows (Rogowska et al, 2009;Patra et al, 2007). Although further research is necessary, the concentrations of the same elements in different tissues could indicate mutual reflectance and be complementary for assessment of corresponding heavy metal exposure, as was also suggested in human studies (Xing et al, 2017).…”

Section: Discussionsupporting

confidence: 86%

Blood and hair as non-invasive trace element biological indicators in growing rabbits

et al. 2019

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The suitability of blood and hair as non-invasive tools to monitor trace element contents was studied in 48 Hyla male growing rabbits. Three diets with increasing organic selenium (Se) addition (0.1, 0.5 and 2.5 mg/kg) were used to induce alterations in the concentrations of trace elements vs. an unsupplemented diet. In blood, a linear decrease in Co (P<0.001), Cu (P<0.001), Mn (P<0.05), Zn (P<0.05), Sb (P<0.001), As (P<0.001), Cr (P<0.001), Mo (P<0.001), Ni (P<0.001) and Cd (P<0.001) concentrations with increasing dietary Se was observed. In hair, a cubic effect of dietary Se on Co (P<0.01), Cu (P<0.05), Mn (P<0.001), Pb (P<0.05), Mo (P<0.05) and Cd (P<0.05) concentrations was found, while As, Cr and Ni concentrations decreased linearly (P<0.01, P<0.01 and P<0.001, respectively) with increasing dietary Se. Selenium was negatively correlated to Sb, As, Cr, Mo, Ni and Cd, (P<0.001) in blood, and to As (P<0.05), Cr, Ni (P<0.01) and Pb (P<0.05) in hair. The contents of Se, As, Cr and Ni in blood were highly correlated (P<0.001) to those in hair. Blood appeared to be more sensitive than hair in detecting small changes in the trace element profile in rabbits, as was indicated by the discriminant analysis. In conclusion, blood and hair can be suitable biological indicators of essential, toxic and potentially toxic trace element status in rabbits, particularly when used complementarily.

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Section: Discussionsupporting

confidence: 86%

Blood and hair as non-invasive trace element biological indicators in growing rabbits

et al. 2019

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“…A multivariate analysis confirmed that sex, age, and smoking habit significantly influence urine Cd, and we also made the analysis to detect whether the blood Cd level was associated with gender and age [17]. No statistically significant differences were found in different gender and age groups in this study, perhaps because the quantity of samples was relatively limited [18]. Diet and drinking water are identified as the primary sources of Cd exposure in the general populations [19].…”

Section: Discussionsupporting

confidence: 55%

Assessment of the Cadmium Exposure in the Blood, Diet, and Water of the Pumi People in Yunnan, China

Wang

Feng

Wang

et al. 2015

Biol Trace Elem Res

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Cadmium (Cd) is considered as one of the most toxic and carcinogenic heavy metals. Accumulation of Cd in the human body can cause multiorgan dysfunction. Long-term irrational mining activities have led to serious Cd pollution in soil, water, and even agricultural products. Therefore, evaluating the Cd exposure levels of people living in mining areas is of great importance. In the current study, we chose the Pumi people who lived in Jinding and Tongdian towns of Lanping county in Yunnan province, China, to do the on-site nutritional epidemiology investigation and laboratory detection. We analyzed the content of the Cd in peripheral blood and mixed dietary, as well as water samples in the Pumi residents of the two towns. Results showed that the blood Cd levels of people in Jinding town, which is nearer the mining district, were statistically significantly higher than those in Tongdian town. The P 50 of blood Cd level of the two towns was 0.64 ng/mL. In addition, the P 50 of the mixed diet of the two towns was 8.32 μg/kg. There was a weak correlation between blood Cd levels and Cd exposure in the mixed diet, PTDI, and PTWI of the Pumi people. In addition, higher concentrations of Cd were observed in the water of Jinding town, indicating people in Jinding town risking more Cd exposure. These results indicated that diet and water are critical factors of Cd exposure for the residents and the nearer people living to mining district risking the more Cd exposure.

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“…The blood Cd concentrations of the 5682 residents living near the 38 abandoned metal mines in Korea were found to be 1.60 μg/L, and those of the residents living within a 2 km radius of the abandoned mine were found to be 1.87 μg/L, which are higher than those of the residents living outside of the 2 km radius (1.31 μg/L) (Park et al 2014). The blood Cd concentration of the US general population aged ≥20 years was 0.36–0.47 μg/L (CDC CDC 2009), while that of the Canadian general population aged ≥20 years was 0.35–0.49 μg/L.…”

Section: Resultsmentioning

confidence: 99%

“…Residents living near the abandoned metal mines were people aged ≥65 years who had lived in the area for 40 years or longer (Park et al 2014). There is a high likelihood that residents have been exposed to the pollutants as they have resided in the areas for a long time after development and abandonment of the mines.…”

Section: Introductionmentioning

confidence: 99%

Exposure factors of cadmium for residents in an abandoned metal mine area in Korea

Ahn

Chang

Lee

et al. 2016

Environ Geochem Health

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This study evaluated blood and urine cadmium (Cd) levels and human exposure factors for residents in an abandoned metal mine in Korea. We collected blood, urine, soil, water, and rice grain samples to analyze Cd concentrations and analyzed heavy metal concentration patterns in soil. We estimated the major exposure factor of Cd through non-carcinogenic risk assessment depending on exposure routes. The blood Cd concentration in the case group was 5.33 μg/L (geometric mean), significantly higher than that in the control group (1.63 μg/L, geometric mean). Urine Cd concentrations were also similar. The Cd concentrations in paddy soil (1.29 mg/kg) and rice grains (0.14 mg/kg) in the study area were higher than those in the control area (0.91 and 0.07 mg/kg, respectively). The analysis of heavy metal concentration in soil showed that the Cd levels in agricultural soil in the case group were attributable to the mine. The hazard quotient (HQ) of Cd by rice ingestion in the case group (1.25) was 2 times higher than that in the control group (0.6). We found that the HQ of rice ingestion contributed to more than 97 % of the total HQ, indicating that rice grains were the major exposure source. However, it is likely that the continuous intake of Cd-exposed crops led to chronic exposure among the residents in mine area.

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Blood levels of cadmium and lead in residents near abandoned metal mine areas in Korea

Cited by 21 publications

References 14 publications

Blood and hair as non-invasive trace element biological indicators in growing rabbits

Blood and hair as non-invasive trace element biological indicators in growing rabbits

Assessment of the Cadmium Exposure in the Blood, Diet, and Water of the Pumi People in Yunnan, China

Exposure factors of cadmium for residents in an abandoned metal mine area in Korea

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