Blood Levels of Mepivacaine After Regional Anaesthesia

Single-Injection Brachial Plexus Anesthesia for Arteriovenous Fistula Surgery of the Forearm: A Comparison of Infraclavicular Coracoid and Axillary Approach

“…Similar complications have been reported before. 6,7 In our study, the total dose of epinephrine was relatively large, 168 to 240 g (i.e., larger than suggested by Raj and coworkers 8 as the maximum recommended dose of 1.5 g/kg/10 min). Intravascular injection of the local anesthetic solutions, a possible complication of both the axillary and the lateral infraclavicular approaches, 4,9,10 did not occur in our patients.…”

Plasma Concentrations of Local Anaesthetics After Interscalene Brachial Plexus Block

“…Considering that large doses of local anaesthetics are required for brachial plexus block compared with most other regional procedures, it is surprising that there is relatively little published data on plasma concentrations following this particular procedure, although several reports are available on mepivacaine (Dhuner et al, 1965;Harley and Gjessing, 1969;Tucker et al, 1972). The plasma concentrations found here were higher than those reported following axillary block with lignocaine and adrenaline (Mazze and Dunbar, 1966) or with bupivacaine and adrenaline (Yoshikawa, Mima and Egawa, 1968).…”

An unusual toxic reaction to axillary block by mepivacaine with adrenaline

“…An axillary block performed in our patient with 600 mg of mepivacaine without adrenaline at another hospital four years previously, did not produce any toxic symptoms. A similar patient, who had a brachial plexus block on two occassions, once without and once with adrenaline, was described by Dhuner et al (7). No complications occured after the first block, but 10 min after performance of the second block the patient shivered, reported palpitations and was agitated.…”