Blood lipids in middle-aged British men.

Thelle, Dag S.; Shaper, A. G.; Whitehead, T. P.; Bullock, D G; Ashby, Deborah; Patel, Indravadan H.

doi:10.1136/hrt.49.3.205

Cited by 112 publications

(47 citation statements)

References 21 publications

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“…Detailed information on blood lipid measurements have been published. 18 Adjustments were made for the marked diurnal variation in serum triglyceride concentration Blood glucose: Glucose was analysed by a glucose oxidase method using automated analyser (Technicon SMA 12/60). Diurnal variation in glucose levels was modest and no adjustments were made for diurnal variation.…”

Section: Blood Lipidsmentioning

confidence: 99%

Hypertension, serum insulin, obesity and the metabolic syndrome

et al. 1998

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Background and aims: In recent years it has been proposed that hypertension is part of a cluster of metabolic risk factors (syndrome X) involving hyperlipidaemia and hyperglycaemia, with hyperinsulinaemia as the common link. This study has investigated: (1) the prevalence of the metabolic syndrome and its component variables and their relationship to body mass index (BMI) and non-fasting insulin levels in a general population; and (2) the distribution and clustering of metabolic variables in normotensives and hypertensives. Methods: Cross-sectional study of 5222 men aged 40-59 years with no history of coronary heart disease (CHD), diabetes mellitus or stroke drawn from general practices in 18 British towns. The men were a subgroup of the 7735 men in the British Regional Heart Study (BRHS) cohort whose baseline non-fasting serum was analysed for insulin, using a specific ELISA method. Main outcome measures: Hyperinsulinaemia, hyperglycaemia, high serum total cholesterol, high triglyceride and hyperuricaemia were defined as the top 20% of the distribution in the 5222 men. Low HDL-cholesterol was defined as the bottom 20%. Results: BMI and non-fasting insulin were both significantly and strongly associated with non-diabetic hyperglycaemia, lipid abnormalities (HDL-cholesterol, triglyceride and total cholesterol) and hyperuricaemia. BMI was strongly associated with hypertension whereas

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Section: Blood Lipidsmentioning

confidence: 99%

Hypertension, serum insulin, obesity and the metabolic syndrome

et al. 1998

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“…Previous studies are disparate in their findings regarding smoking and serum TC. There have been reports of a positive association14), a negative association za> and no association a 10) Thelle et al 14) reported a positive association between smoking and serum TC in their multi-center cross-sectional study, but they did not adjust for any potential confounding factors. Our inverse association between cigarette smoking and serum LDL-C was different from the previous observation of null association a 10, 25) BMI was found to be the most important factor for atherogenicity in serum lipid profile.…”

Section: Discussionmentioning

confidence: 99%

“…10, 11); alcohol consumption and physical activity increase serum HDL-C concentration, thereby conferring an antiatherogenic property [9][10][11][12][13][14][15] However, few studies have evaluated the relative importance of these factors in the variation of atherogenicity of serum lipid profile 8.10.16) We investigated the relationship of cigarette smoking, alcohol use, recreational physical activity and obesity with serum lipid atherogenicity in middle-aged Japanese men.…”

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confidence: 99%

Relationship of Cigarette Smoking, Alcohol Use, Recreational Exercise and Obesity with Serum Lipid Atherogenicity: A Study of Self-Defense Officials in Japan

Umeda

Kono

Sakurai

et al. 1998

Journal of Epidemiology

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“…High density lipoprotein cholesterol level is also associated with physical activity 17,22 . Furthermore, the proportion of energy intake derived from saturated fat and animal protein is an important determinant of differences in blood cholesterol level among populations 5 .…”

Section: Introductionmentioning

confidence: 99%

Blood lipid associations in 18 year-old men

1992

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POLETTO, L. et al. Blood lipid associations in 18 year-old men. Rev. Saúde públ, S. Paulo, 26: 316-20, 1992. The association of cigarette smoking, physical activity at work, and social class with total cholesterol and with high and low density lipoprotein cholesterol were examined in a random sample of 238 males, of 18 years of age, of Rosario, Argerntina. The mean (mg/dl) total serum cholesterol of the whole sample was 174.7, the high density lipoprotein cholesterol 52.8, and the low density lipoprotein cholesterol 121.5. Black tobacco consumers, evenly distributed by social class, had higher levels of total and low density lipoprotein cholesterol. Total cholesterol was higher in the high social class, differently from what smokers' distribution by social class, would lead one to expect. While a highly negative association was found between social class and physical activity at work, there were no significant diferences in lipoprotein levels between manual and non-manual workers. It is possible that the nutritional differences by social class still prevail over the smoking habit in their influence on the lipoprotein levels in these subjects.

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Blood lipids in middle-aged British men.

Cited by 112 publications

References 21 publications

Hypertension, serum insulin, obesity and the metabolic syndrome

Hypertension, serum insulin, obesity and the metabolic syndrome

Relationship of Cigarette Smoking, Alcohol Use, Recreational Exercise and Obesity with Serum Lipid Atherogenicity: A Study of Self-Defense Officials in Japan

Blood lipid associations in 18 year-old men

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