Background: Excessive blood loss is the most frequently encountered perioperative problem in maxillary surgery, sometimes necessitating blood transfusion. Objective: The aim of the present contribution is to review the relationship between different types of orthognathic procedures and the related blood loss in the literature published between 1976 and 2012. Data Sources: The orthognathic literature was searched from 1976 to 2012 to determine the relationship between different types of orthognathic procedures and the related blood loss, duration of surgery and/or transfusion need. Study Selection: articles containing clear information on allocation of operation time AND/OR blood loss AND/OR transfusion were included. Data Extraction: information on operation time, blood loss, transfusion, and orthognathic surgery was extracted. Data Synthesis: Different descriptions of procedures and techniques are grouped together in a concise and coherent way, this result in number of categories per label, using this grouping various targeted questions are exploited and answered.