Blood pressure and stature inHelicobacter pyloripositive and negative persons

Abstract

To evaluate vital signs and body indices in Helicobacter pylori (H. pylori) positive and negative persons. A total of 22 centres entered the study. They were spread over the whole country, corresponding well to the geographical distribution of the Czech population. A total of 1818 subjects (aged 5-98 years) took part in the study, randomly selected out of 38147 subjects. H. pylori infection was investigated by means of a 13C-urea breath test. Data on height, weight, systolic and diastolic blood pressure and heart rate were collected at the clinics of general practitioners. The overall prevalence of H. pylori infection was 30.4% (402/1321) in adults (≥ 18 year-old) and 5.2% (26/497) in children and adolescents (≤ 17 year-old). Once adjusted for age and gender, only a difference in body mass index remained statistically significant with H. pylori positive adults showing an increase of 0.6 kg/m(2) in body mass index. Once adjusted for age and gender, we found a difference in height between H. pylori positive and H. pylori negative children and adolescents. On further adjustment for place of residence, this difference became statistically significant, with H. pylori positive children and adolescents being on average 3.5 cm shorter. H. pylori positive adults were significantly older compared to H. pylori negative subjects. Once adjusted for age and gender, H. pylori infection had no impact on body weight, body mass index and vital signs either in adults or children and adolescents. Chronic H. pylori infection appeared to be associated with short stature in children. H. pylori infection did not influence blood pressure, body weight and body mass index either in adults or children and adolescents.

Role of Helicobacter pylori Infection in Body Height of Adult Dyspeptic Patients

“…A role of H. pylori in determining growth retardation in childhood has been hypothesized by several authors [26][27][28][29][30]; however, published results are conflicting. Kopacova et al in the Czech population demonstrated an association between chronic H. pylori infection and short stature in children [29].…”

“…A role of H. pylori in determining growth retardation in childhood has been hypothesized by several authors [26][27][28][29][30]; however, published results are conflicting. Kopacova et al in the Czech population demonstrated an association between chronic H. pylori infection and short stature in children [29]. Additional studies reported a statistically significant association between H. pylori infection, low socioeconomic status, especially overcrowding in childhood, malnutrition, and short stature [31,32].…”

Central obesity is associated with helicobacter pylori infection: a large-scale cross-sectional retrospective study in West China

“…But the relationship between H. pylori infection and obesity remains controversial [2][3][4][5][6][7]. Some studies identified a positive correlation [3,[8][9][10], while others found a negative correlation [4,7] or even no correlation [2,11]. A meta-analysis of 18 observational studies involving over 10,000 subjects found a higher body mass index (BMI) among H. pylori-positive subjects compared with H. pylori-negative subjects [12].…”

Helicobacter pylori Infection in Pediatrics

“…H. pylori infection did not influence blood pressure, body weight, or body mass index either in adults or in children and adolescents [24].…”

“…Chronic H. pylori infection appeared to be associated with short stature in children. H. pylori infection did not influence blood pressure, body weight, or body mass index either in adults or in children and adolescents .…”