Blood Pressure Categories and Cardiovascular Risk Factors in Japan: The Jichi Medical School (JMS) Cohort Study

Abstract

Few studies have reported on risk factors by blood pressure categories based on antihypertensive treatment in the general population. We examined the associations between blood pressure categories and other risk factors in Japan. Cross-sectional study, multicenter population-based study was designed. A total of 11,302 men and women were eligible. Data were obtained from April 1992 to July 1995 in 12 rural districts in Japan. Subjects were divided into three categories: normotensives (with blood pressure <140/90 mmHg), treated hypertensives (antihypertensive treatment regardless of current blood pressure), and nontreated hypertensives (blood pressure >or=140/90 mmHg without hypertensive treatment). The proportions of normotensives, treated hypertensives, and nontreated hypertensives were 63%, 10%, and 27% among men, and 67%, 13%, and 20% among women, respectively. Total cholesterol, triglyceride, blood glucose, and body mass index were higher in treated or nontreated hypertensives than in normotensives. Fibrinogen, factor VIIc, and physical activity index were higher in treated hypertensives than in normotensives. High-density lipoprotein (HDL) cholesterol was higher in normotensives than in treated or nontreated hypertensives in women; but no tendency was shown in men. The proportions of dyslipidemia, impaired glucose tolerance, and metabolic syndrome were significantly higher in treated and nontreated hypertensives than in normotensive men and women. In conclusion, cardiovascular risk factors were higher in hypertensives with or without treatment than in normotensives in a general population in Japan.

Prevalence of Preexisting Metabolic Syndrome as Defined by Japanese Original Criteria among Patients with Non-fatal Myocardial Infarction

“…This study showed that 79.2% of the subjects had two or more preexisting risk factors and only two subjects had no risk factor. This proportion was similar to the results of the previous studies which evaluated the number of risk factors of MI among patients without MetS (28)(29)(30). These findings suggest that a long duration of multiple risks may cause CHD in Japanese.…”

Risk Charts Illustrating the 10-year Risk of Myocardial Infarction among Residents of Japanese Rural Communities: The JMS Cohort Study

“…18 – 20 In this article we utilize data from the JMS Cohort Study to develop risk assessment charts for MI.…”

Predictors for Prehypertension in Patients with Impaired Glucose Tolerance

“…, Takayuki MASAKI 2) , Eri ONO 1) , Takeshi ETO 1) , Tetsu IWAO 1) , Nobuoki ESHIMA 3) , Tetsunori SAIKAWA 4) , and Hironobu YOSHIMATSU 2) Introduction Hypertension has been recognized as a major risk factor for several cardiovascular diseases (1)(2)(3). In its seventh report, the 2003 Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-7) defined a new set of guidelines for the prevention and management of hypertension.…”