Blood pressure goal attainment in multi-ethnic Asian patients with hypertension and dyslipidaemia in primary care

Abstract

Introduction: Hypertension and dyslipidaemia are major risk factors for cardiovascular diseases, and achieving treatment goals mitigates such risks. This study determined demographic and medication-related factors associated with blood pressure (BP) goal attainment in patients with concomitant hypertension and dyslipidaemia. Methods: This paper consisted of a sub-analysis of the Lipid HEALTH study, a questionnaire survey focusing on adult Asian patients with both dyslipidaemia and hypertension. Intervieweradministered questionnaire was used to obtain information on demographic and clinical information. Laboratory and prescription data was retrieved from electronic health records. BP goals were defined by international guidelines. Data was audited and analysed, followed by logistic regression analysis to identify factors determining BP goal attainment. Results: The complete data of 851 included patients were analysed; 49.7% of them attained their BP goals. 37% were on monotherapy, 57.6% on two or more BP-lowering medications, and 5.5% had no pharmacologic treatment. Among those on pharmacotherapy, 51.2% failed to achieve BP goals. Calcium channel blockers were the most frequently prescribed medications. Attainment of BP goals was significantly associated who had no type 2 diabetes mellitus (DM) (OR 2.27; 95% CI 1.61-3.13); attained low-density lipoprotein cholesterol (LDL-C) goal (OR 2.02; 95% CI 1.45-.81); were solely on dietary control (OR 2.19; 95% CI 1.09-4.39); and received monotherapy (OR 1.71; 95% CI 1.18-2.48). Conclusion: BP treatment goals were attained by half of the patients with dyslipidaemia and hypertension, and half of those on pharmacotherapy. Type 2 DM and LDL-C control were significantly associated with BP goal attainment.

Prescribing patterns and pharmacoeconomic analysis of antihypertensive drugs in South Indian population: A cross-sectional study

“…In this study, out of 650 subjects, 39.54% achieved the target BP. This is in agreement with studies conducted in Singapore which recorded 49.7%[ 9 ] and in Ethiopia 25.6%. [ 10 ] On the other hand, studies conducted in Australia[ 11 ] reported higher BP control.…”

Characteristics of serum lipid levels in patients with hypertension: a hospital-based retrospective descriptive study

“…Some studies suggested that abnormal serum lipid levels may contribute to hypertension and that correcting serum lipid abnormalities may help control blood pressure. 18 19 Dyslipidaemia is often still neglected in patients with hypertension, especially in those at higher risk of cardiovascular and cerebrovascular diseases. 20 Therefore, it is of great importance to study the serum lipid profiles of patients with hypertension in the prevention and treatment of cardiovascular and cerebrovascular diseases.…”

“…Patients with hypertension often have dyslipidaemia. Some studies suggested that abnormal serum lipid levels may contribute to hypertension and that correcting serum lipid abnormalities may help control blood pressure 18 19. Dyslipidaemia is often still neglected in patients with hypertension, especially in those at higher risk of cardiovascular and cerebrovascular diseases 20.…”

Comparing and determining factors associated with hypertension self-care profiles of patients in two multi-ethnic Asian countries: cross-sectional studies between two study populations

“…In Singapore, 49.7% of patients treated for hypertension in primary care were reported with good blood pressure (BP) control. 7 While in Malaysia, the proportion of patients with good hypertension control is lower at 37.4%. 8 The differences in the proportion of good BP control warrants a comparison of their health behaviour profiles in the two countries as they have similar multi-ethnic background and culture.…”