Blood pressure, hypertension and correlates in urbanised workers in Ibadan, Nigeria: a revisit

Kadiri, S; Walker, O; Bl, Salako; Akinkugbe, O. O.

doi:10.1038/sj.jhh.1000722

Cited by 82 publications

(91 citation statements)

References 18 publications

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“…Alcohol consumption was similarly found not to impart any excess risk on the MHT group, although it is a clear risk factor for hypertension in Nigerians. 24,26 Oral contraceptives were infrequently used, and analgesic use was not evaluable because of unreliable reporting. Oral contraceptives use was not associated with MHT, in agreement with a recent study, which showed that MHT was not related to contraceptives use, 27 but not in agreement with others.…”

Section: Discussionmentioning

confidence: 99%

Factors influencing the development of malignant hypertension in Nigeria

2000

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Hypertension prevalence rates remain comparatively low in Nigeria, although the associated morbidity and mortality including that due to malignant hypertension (MHT) is considerable. To determine the factors that may be associated with the development of MHT we compared 74 patients with essential MHT (age 48 ؎ 9 years, 59 male, blood pressure (BP) 234 ؎ 31/140 ؎ 17 mm Hg) with 74, age, gender and BP-matched patients with essential benign hypertension (BHT) (49 ؎ 8 years, 60 male, 227 ؎ 26/136 ؎ 15 mm Hg). Body mass index was higher in the MHT group by 1.3 (95% Cl: 0.5 to 2.1, P Ͻ 0.01). In the subset (25 MHT, 43 BHT) in whom hypertension had been diagnosed before presentation, duration of hypertension was shorter (P Ͻ 0.05) in the Keywords: malignant hypertension; risk factors; black Nigerians IntroductionMalignant hypertension (MHT) remains a common condition in some populations, 1,2 and although its prognosis may be improving, it is still associated with considerable morbidity.1 Very high blood pressure (BP) is required for the development of MHT, but since the BP alone does not distinguish non-malignant, benign hypertension (BHT) from MHT and both conditions may exist at similar BP, other factors are clearly in operation.3-5 Some of these may relate to the kidney or vasculature, 3 the immune system 4 and to external or environmental differences.5 It may be possible to manipulate these external variables and prevent the transition to the malignant phase. Prevention of the transition to the malignant phase would reduce the morbidity and mortality attributable to hypertension, since the prognosis is worse in MHT. 6,7 This study aims at identifying these external factors in black Nigerian hypertensives, a group that is arguably underserved. Patients and methodsA record has been kept of the cases of MHT seen in over 10 years. MHT was diagnosed on the basis of severe hypertension with bilateral retinal exudates and haemorrhages with or without papilloedema. 8,9 A detailed account of the clinical presentation of some of the patients has been published elsewhere. 10Patients with secondary causes of hypertension were excluded. Secondary hypertension was excluded on the basis of history, physical examination, urine examination, serum electrolytes, renal ultrasound and renal arteriography as presented in the earlier study. 10 The presence of primary renal disease was suggested by the presence of urinary red cells, red and white cell casts, granular casts and proteinuria up to 1.5 g/24 h. 11 Where there was some doubt as to the cause of the hypertension, such patients were excluded. Accordingly, 74 patients were considered to have primary MHT. These patients were compared with 74 age, gender and BPmatched controls with benign essential hypertension newly presenting at the hypertension clinic. They necessarily had repeatedly high BP readings and grade 3 hypertension. 12Age, gender, body mass index (BMI), socio-economic group, BP, serum creatinine, history of smoking and alcohol use, perception of stress, known duration o...

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Section: Discussionmentioning

confidence: 99%

Factors influencing the development of malignant hypertension in Nigeria

2000

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“…Using the revised cut-off of 140/90 mmHg, a revised prevalence rate of 17-20 % has been reported. 11 In another population-based survey, a prevalence rate of 14.5 % was observed. 12 In a meta analysis of studies on prevalence of hypertension in Nigeria, prevalence rates ranges from 12.4 to 34.8 % among adults in Nigeria.…”

Section: Introductionmentioning

confidence: 94%

Prevalence of Hypertension among Urban Slum Dwellers in Lagos, Nigeria

Daniel

Adejumo

et al. 2013

J Urban Health

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Urban slum dwellers are not only prone to develop communicable diseases but also to non-communicable disease (NCDs). The extent and magnitude of NCDs among slum dwellers is largely unknown in Nigeria. A total of 964 adults aged 20-81 years (male 330 and female 634) residing in the urban slum of Ajegunle in Lagos State, Nigeria were studied to determine the prevalence of hypertension and associated factors. The overall prevalence of hypertension was 38.2 %. Of the 368 respondents identified as having hypertension, only 50 (5.2 %) respondents were previously aware of their diagnosis. Of the 50 known hypertensive patients, 48(96 %) had poor control of their high blood pressure. The socio-demographic factors significantly associated with hypertension status were age, sex, education, religion, BMI, and marital status. The study concludes a high prevalence of hypertension among urban slums dwellers in Lagos. The need for government to develop policies for the control of hypertension, improve access to early diagnosis and provide an enabling socioeconomic environment while promoting healthy living.

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“…Adjusting these, with the cut-off point of 140/90mmHg, these results would lead to a current prevalence rate of 17 to 20% (7.8million) 10 It is recommended from this study, that as much as practicable, hypertensive patients be evaluated with Doppler echocardiogram in order to detect the early effects of hypertension on the heart, especially as represented by diastolic dysfunction, with a view to affecting the management outcome.…”

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confidence: 99%