Blood Pressure in Adult Patients With Congenital Heart Disease

Murakami, Tomoaki; Kobayashi, Hironobu; Nagamine, Hiroki; Shiraga, Kazuhiro; Fukuoka, Shoji; Higashi, Kouji; Tateno, Shigeru; Kawasoe, Yasutaka; Nakajima, Hiroyuki; Aotsuka, Hiroyuki; Niwa, Koichiro

doi:10.1016/s0735-1097(15)60521-6

Cited by 2 publications

(1 citation statement)

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“…The prevalence of hypertension was lower in our ACHD patients49) compared to the general Japanese population (15.1 vs. 26.5% in males). Regarding recent paper on blood pressure in 100 ACHD patients (age, 37.0±15.0 years),73) average systolic blood pressure was 117.7±20.1 mmHg and diastolic blood pressure was 69.7±14.3 mmHg with central systolic blood pressure of 119.9±21.5 mmHg, respectively. Hypertension was observed in 16 (16%).…”

Section: Risk Factors For Coronary Artery Disease and Metabolic Syndrmentioning

confidence: 94%

Metabolic Syndrome in Adult Congenital Heart Disease

Niwa

2019

Korean Circ J

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In adult congenital heart disease (ACHD), residua and sequellae after initial repair develop late complications such as cardiac failure, arrhythmias, thrombosis, aortopathy, pulmonary hypertension and others. Acquired lesions with aging such as hypertension, diabetes mellitus, obesity can be negative influence on original cardiovascular disease (CVD). Also, atherosclerosis may pose an additional health problem to ACHD when they grow older and reach the age at which atherosclerosis becomes clinically relevant. In spite of the theoretical risk of atherosclerosis in ACHD due to above mentioned factors, cyanotic ACHDs even after repair are noted to have minimal incidence of coronary artery disease (CAD). Acyanotic ACHD has similar prevalence of CAD as the general population. However, even in cyanotic ACHD, CAD can develop when they have several risk factors for CAD. The prevalence of risk factor is similar between ACHD and the general population. Risk of premature atherosclerotic CVD in ACHD is based, 3 principal mechanisms: lesions with coronary artery abnormalities, obstructive lesions of left ventricle and aorta such as coarctation of the aorta and aortopathy. Coronary artery abnormalities are directly affected or altered surgically, such as arterial switch in transposition patients, may confer greater risk for premature atherosclerotic CAD. Metabolic syndrome is more common among ACHD than in the general population, and possibly increases the incidence of atherosclerotic CAD even in ACHD in future. Thus, ACHD should be screened for metabolic syndrome and eliminating risk factors for atherosclerotic CAD.

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Section: Risk Factors For Coronary Artery Disease and Metabolic Syndrmentioning

confidence: 94%