Blood product transfusions are associated with an increase in serum (1-3)-beta-<scp>d</scp>-glucan in infants during the initial hospitalization in neonatal intensive care unit (NICU)

Goudjil, Sabrina; Chazal, Christèle; Moreau, F.; Léké, A.; Kongolo, G.; Chouaki, Tayeb

doi:10.1080/14767058.2016.1191064

Cited by 12 publications

(6 citation statements)

References 28 publications

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“…13,24 Indeed, some studied populations in false-positive BDG results as observed in previous studies. 7,8,25 Such factors included the use of cotton gauze during surgery, blood product transfusions, broad-spectrum antibiotics or antifungal therapy 8,17,18 and systemic bacterial infections. For example,…”

Section: Discussionmentioning

confidence: 99%

“…For example, Goudjil et al reported that blood product transfusion were associated with increased BDG value in neonates. 17…”

Section: Discussionmentioning

confidence: 99%

“…Such factors included the use of cotton gauze during surgery, blood product transfusions, broad‐spectrum antibiotics or antifungal therapy 8,17,18 and systemic bacterial infections. For example, Goudjil et al reported that blood product transfusion were associated with increased BDG value in neonates 17 …”

Section: Discussionmentioning

confidence: 99%

“…Also, diagnostic confirmation was not the same in all studies. Several studies reported that extrinsic factors such as bacterial infection, specific antibiotics, surgery or blood products could modify the diagnostic accuracy of the BDG assay 8,17,18 …”

Section: Introductionmentioning

confidence: 99%

“…Several studies reported that extrinsic factors such as bacterial infection, specific antibiotics, surgery or blood products could modify the diagnostic accuracy of the BDG assay. 8,17,18 Because of heterogeneous data about the diagnostic use of serum BDG in newborn infants, we assessed the diagnostic accuracy of the BDG assay according to the cut-off value recommended by the manufacturer for adults and currently used for newborn infants with suspected NIC. We also searched for an optimal cut-off value for the BDG assay for detecting and for ruling out NIC in order to stop empirical antifungal treatments earlier.…”

mentioning

confidence: 99%

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Serum (1 → 3)‐β‐D‐glucan could be useful to rule out invasive candidiasis in neonates with an adapted cut‐off

et al. 2020

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The incidence of proven neonatal invasive candidiasis (NIC) has ranged from 2.6% to 13.2% in children with birth weight of <1500 g and from 6.6% to 26.0% with birth weight of <1000 g. 1,2 Candida albicans and Candida parapsilosis are the most common fungal species in this population. 2 The incidence of NIC has decreased since the 2000s with the control of identified risk factors, improved infection control and the use of fluconazole prophylaxis. 1-5 However, NIC is still associated with high morbidity rates in neonates and mortality rates of about 30%. 2,6 Because of the delay in fungal culture results, with a risk of false-negative findings, the diagnosis is difficult. That's

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