Blood transfusion‐induced posterior reversible encephalopathy syndrome with periodic sharp wave complexes, 14‐3‐3 protein elevation, and the pulvinar sign

Abstract

A 52‐year‐old Japanese woman was admitted to our hospital with consciousness disturbance and convulsions at 10 days after transfusion with 10 U of blood due to severe anemia. Electroencephalography showed periodic sharp wave complexes, cerebrospinal fluid 14‐3‐3 protein levels were elevated, and brain magnetic resonance imaging demonstrated bilateral thalamic hyperintensity. These findings suggested Creutzfeldt‐Jakob disease (CJD); however, her symptoms were resolved with antiepileptic and anti‐hypertensive drugs. We herein report a case of posterior reversible encephalopathy syndrome that occurred after a blood transfusion who showed features compatible with CJD.

Blood transfusion‐induced posterior reversible encephalopathy syndrome presenting severe brain atrophy: A report of two cases

“…She is unable to follow instructions and verbal communication is minimal. We reported the patient's acute medical course previously 5 . She was transferred to a psychiatric hospital for the continuation of medical treatment.…”