“…For example, in a recent study, Magni et al could show that blue light (410–420 nm; 20.6 J/cm 2 , 0.69 W/cm 2 ) induces a quicker healing process in a mouse model. The authors suggested that the photobiomodulation of the wounds with blue light evokes a mast cell response, which, in turn, stimulates an early inflammatory response, angiogenesis, and myofibroblast differentiation [ 59 ]. In patients ( n = 12) with systemic sclerosis skin ulcers, the weekly treatment of the ulcers with blue light (400–430 nm, 120 mW/cm 2 , 7.2 J/cm 2 ), in addition to the standard therapy, showed significant improvements after 8 weeks [ 60 ].…”