Blue light-induced phototoxicity in retinal cells: implications in age-related macular degeneration
Harshini Chakravarthy,
Vasil Georgyev,
Cole Wagen
et al.
Abstract:Sunlight exposure is recognized as a risk factor for the development of age-related macular degeneration (AMD), a common neurodegenerative retinal disease in the elderly. Specifically, the blue light wavelengths within sunlight can negatively impact the physiology of light-sensitive retinal cells, including retinal pigmented epithelium (RPE) and photoreceptors. This review explores blue light-induced retinal degeneration, emphasizing the structural and functional impairments in RPE. The initial section provide… Show more
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