Blue nevus of the oral cavity

Kjærheim, Å; Martinez, M.G.; Montes, Leopoldo F.

doi:10.1016/0030-4220(70)90270-7

Cited by 23 publications

(5 citation statements)

References 6 publications

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“…The majority of nevus cells were wrapped around hy well formed basement memhrane either in part or in full. This finding is in accordance with those of Kjaerheim et al (1970), Nakai & Rappaport (1963), Merkow et al (1969). Basement membrane was not observed by Hernandez (1973) or Silverberg et al (1971) and not mentioned hy Mishima (1970) in their EM studies of the cellular and malignant blue nevi.…”

Section: Nevus Cellssupporting

confidence: 92%

“…An occasional single cilium has been reported in non-ciUated cells of different tissues including skin (Wheatly 1967, Wilson & McWhorter 1963. The single cilium has also been reported in nevus cells of blue nevus (Kjaerheim et al 1970). However, the presence of two cilia (Fig.…”

Section: Nevus Cellsmentioning

confidence: 77%

“…4 and 5) were also observed. These have not been descrihed in earlier studies of hlue or cellular blue nevi (Allegra 1974, Hernandez 1973, Jao et al 1971, Kjaerheim et al 1970, Merkow et al 1969, Mishima 1970, Nakai & Rappaport 1963, Rodriguez & Ackerman 1968, Silverberg et al 1971 ) and in pigmented basal cell carcinoma (Bhawan 1979). Allegra (1974) observed that melanoeytes devoid of Golgi apparatus were not capable of developing mature melanosomes.…”

Section: Nevus Cellsmentioning

confidence: 83%

“…X 36,000. these nevi are neurogenic in origin (Merkow et al 1969, Nakai & Kappaport 1963, while the other theory emphasizes the melanoeytie origiii (Hu 1967, Hernandez 1973, Mishima 1970. The occurrence of these nevi in tissues other than skin (Block et al 1972. Kjaerheim et al 1970, Qizilibash 1973, Tobon & Murphy 1977 certainly favors the neurogenic concept.…”

Section: Stromal Changesmentioning

confidence: 99%

“…However, despite their cellular characteristics and even lymph nodal metastasis, patients with these tumors do very well (Rodriguez & Ackerman 1968). Several electron microseopic studies have been performed (Allegra 1974, Hernandez 1973, Jao et al 1971, Kjaerheim et al 1970, Merkow et al 1969, Mishima 1970, Nakai & Rappaport 1963, Rodriguez & Ackerman 1968, Silverberg et al 1970 but the controversy regarding their histogenesis still exists. The present paper reports ultrastructural features of three cases and reviews the histogenetic aspects of cellular blue nevus.…”

mentioning

confidence: 99%

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Cellular Blue Nevus

1980

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Cellular blue nevus can be clinically and histogenetically confused with malignant melanoma but remains a benign neoplasm of uncertain histogenesis. This paper reports the ultrastructural features of three cases of cellular blue nevus and emphasizes melanosomal alterations, including immature and granular forms, multiple layers of basement membrane around vessels, nerve fibers and tumor cells; endothelial fenestrations and banded structures within the nerve and outside in the stroma. A unifying concept of neural crest derived tumors is presented to better understand the histogenesis of cellular blue nevus.

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Section: Nevus Cellssupporting

confidence: 92%

Section: Nevus Cellsmentioning

confidence: 77%

Section: Nevus Cellsmentioning

confidence: 83%

Section: Stromal Changesmentioning

confidence: 99%

mentioning

confidence: 99%

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Cellular Blue Nevus

1980

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Malignant Blue Nevus

Hernandez¹

1973

Arch Dermatol

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The ultrastructure of benign pigmented naevi and melanocarcinomas in man

Curran¹,

McCann²

1976

The Journal of Pathology

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Nine benign pigmented naevi and 16 melanocarcinomas (malignant melanomas) were studied by light and transmission electron microscopy and the fine structure of benign and malignant melanocytes is described. It was found that malignant melanocytes generally exhibit a range of abnormalities of structure of nuclei and cytoplasmic organelles which distinguish them clearly from their benign counterparts. Of the abnormalities, those affecting the specific organelle of the melanocyte, the melanosome, were the most constantly present. No firm evidence was found for the existence of two types of melanosome or two types of melanocarcinoma. Although electron microscopy is capable of showing in great detail within individual melanocytes many changes which are clearly associated with malignancy, the technique does not appear to offer significant advantages over light microscopy in determining the diagnosis and prognosis in this group of conditions.

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Blue nevus of the oral cavity

Cited by 23 publications

References 6 publications

Cellular Blue Nevus

Cellular Blue Nevus

Malignant Blue Nevus

The ultrastructure of benign pigmented naevi and melanocarcinomas in man

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