Blueberries and their bioactives in the modulation of oxidative stress, inflammation and cardio/vascular function markers: a systematic review of human intervention studies

Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome – results from a six-month, double-blind, randomized controlled trial

“…In our previous publications from the C ardiovascular, I nsulin R esistance, C ognition and L ung function in m E tabolic S yndrome study (CIRCLES) trial (from which these current data are derived), we showed that freeze-dried blueberries (1 cup/d) improved 24 h postprandial and 6 mo chronic cardiometabolic health in participants with MetS [ 17 , 18 ]; supporting the benefits recognized in non-MetS populations [ 19 ]. Thus, increasing anthocyanin-rich blueberry intake is considered an exemplary dietary strategy to establish whether cognitive and cardiometabolic function benefits are aligned in MetS.…”

Daily blueberry consumption for 12 weeks improves endothelial function in postmenopausal women with above-normal blood pressure through reductions in oxidative stress: a randomized controlled trial

“…Several investigators have explored the effects of blueberry consumption on biomarkers of oxidative stress and antioxidant defense, and reported results have been mixed. 91 We previously demonstrated reductions in blood concentrations of 8-hydroxydeoxyguanosine, a marker of DNA damage, following 4 weeks of daily consumption of 22 g freeze-dried blueberry powder in postmenopausal women with above-normal blood pressure; 92 however, values returned to baseline levels at 8 weeks and other blood biomarkers of oxidative stress and antioxidant defense were unchanged. Basu et al 93 observed reductions in blood biomarkers of oxidative stress following 8 weeks of 50 g daily blueberry consumption in adults with metabolic syndrome.…”

The Research Progress of Extraction, Purification and Analysis Methods of Phenolic Compounds from Blueberry: A Comprehensive Review

“…A daily intake of blueberries (about 1/3 cup) can prevent the onset of chronic diseases, such as obesity, diabetes, atherosclerosis, etc. [6]. This review summarizes the extraction, purification, and detection techniques of phenolic compounds in blueberries.…”