Blueberry intervention improves metabolic syndrome risk factors: systematic review and meta-analysis

Beneficial effects of blueberry supplementation on the components of metabolic syndrome: a systematic review and meta-analysis

“…110 In terms of waist circumference, body weight, BMI, blood glucose and HOMA-IR, the results of the two studies are similar. The Carvalho et al review had 18 studies, of which only 12 were included in the meta-analysis, 110 while our review had 25 studies and 21 were included in the meta-analysis.…”

“…106,108,109 Unlike our study, in a recent systematic review and metaanalysis by Carvalho et al, it was reported that blueberry supplementation, only had significant effects on lipid profile and diastolic blood pressure, among MetS componens, while it did not have any significant effects on systolic blood pressure, blood insulin and body weight. 110 In terms of waist circumference, body weight, BMI, blood glucose and HOMA-IR, the results of the two studies are similar. The Carvalho et al review had 18 studies, of which only 12 were included in the…”

Effects of a (poly)phenol-rich supplement on anthropometric, biochemical, and inflammatory parameters in participants with morbid obesity: Study protocol for a randomised controlled trial

“…There are Scientific Opinion reports that support the safety of green tea catechins, (poly)phenols from olives (hydroxytyrosol and derivates) and resveratrol for human consumption [ [42] , [43] , [44] ]. As per other compounds, i.e., anthocyanins from blueberries and citrus fruit flavonoids (including hesperidin), different interventional studies in humans have reported safe doses or no adverse effects [ [45] , [46] , [47] ] [ [45] , [46] , [47] ] [ [45] , [46] , [47] ]. Ferulic acid has shown low levels of toxicity in animal models [ 48 ] and recent literature has linked this compound to low toxicity in humans [ 49 ].…”

Improving Blueberry Fruit Nutritional Quality through Physiological and Genetic Interventions: A Review of Current Research and Future Directions

“…The most significant correlations that have emerged from research involving human and animal studies are between high blueberry intake and reduced risk of heart disease, type 2 diabetes and visual deterioration, less weight gain and slower rates of cognitive decline (reviewed in [ 6 , 7 , 8 , 30 , 59 ] and references therein). A systematic review and meta-analysis investigating the effect of blueberry intervention on metabolic syndrome risk factors revealed that blueberry intervention decreased total cholesterol and low-density lipoprotein (LDL) levels as well as diastolic blood pressure [ 60 ]. An investigation into blueberry effects in adults suffering from knee osteoarthritis revealed that daily incorporation of blueberries in diet reduced pain and stiffness and improved functionality [ 61 ].…”

“… Health benefits of blueberry consumption. The most significant health-related benefits of blueberry are based on the antioxidant and anti-inflammatory actions of the phytochemicals, mainly anthocyanin, contained in the fruit [ 6 , 7 , 8 , 30 , 59 , 60 , 61 , 62 , 63 ]. …”