Blurred vision due to choroidal metastasis as the first manifestation of lung cancer: A case report

Abstract

BackgroundReduction in visual acuity combined with blurred vision is rarely the first sign of lung cancer and very few cases have been announced globally.Case presentationA case of a 46-year-old man who admitted with blurred vision is presented. His medical history, apart from a mild gastritis under treatment was negative. Ocular examination revealed a decrease in visual acuity due to a choroidal tumor. Further image body scans demonstrated a right lung lesion with dissemination to other organs. Diagnosis of a non-small cell lung cancer established after a VATS biopsy carried out.ConclusionBlurred vision due to choroidal metastasis as the primary symptom of lung cancer is very uncommon. A great index of suspicion is essential when a choroidal lesion appears.

Positron emission tomography is moderately useful in the diagnosis of orbital metastasis

“…Choroidal metastasis, which is seen rarely, is most commonly seen in breast and lung cancers. The incidence of ocular metastases of lung cancers has been reported to be 2-7% in the literature [9]. The diagnosis of ocular metastases is based on clinical findings supported by imaging techniques [9].…”

Choroidal metastasis as the first sign of bronchioloalveolar lung cancer: case report

“…The reason for this unusual site to be target for secondary metastasis from lung cancer is generally unknown. It is, however speculated that is high vascularity may consist a reasonable explanation (1) . The other frequent sites of choroidal metastasis are alimentary tract cancers, prostate, skin melanoma, kidneys, contralateral choroidal melanoma, thyroid and testis (5) .…”

“…It is reported that 22% of patients diagnosed with CM had a concurrent diagnosis of central nervous system metastasis. Differential diagnosis includes primary choroidal melanomas, benign lesions such as hemangioma, and inflammatory granulomas (1) . Systemic chemotherapy can lead to total involution of the CM with improvement of the visual acuity (7) .…”

“…The majority of cases involves end-stage patients (1) . Metastatic tumors are the most common intraocular malignancies, and choroid is by far the most common site for intraocular malignancies.…”

Juxtapapillary Tumor as Lung Cancer’s First Manifestation

“…The differential diagnosis includes primary melanomas, benign lesions such as hemangioma and inflammatory granulomas [11]. The diagnostic investigation of the referred case included the following complementary tests: FAF, FAG, OCT, ocular USG, X-ray, abdominal USG, MRI and lung biopsy through thoracotomy.…”