Blurring of vision as the only symptom in an undiagnosed case of chronic myeloid leukemia in the COVID-19 era

Gumaste, Priyanka; Vairagyam, Rajalingam

doi:10.4103/ijo.ijo_3629_20

Cited by 4 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The commentaries and editorials published by the respected Editor IJO, and stalwarts of Indian Ophthalmology opened channels for deeper insight and a better understanding of the impact of COVID-19 on clinical ophthalmology with their expert inputs. The least were perspectives,[ 24 ] consensus criteria,[ 25 ] ophthalmic images,[ 26 ] and photo assay[ 27 ] with 1 (0.43%) each. The main reasons behind this could be a lack of definitive corelating evidence with COVID-19 or a chance finding.…”

Section: Discussionmentioning

confidence: 99%

“…The probable reasons for maximum general ophthalmology publications were sharing of general consensus guidelines by AIOS, sanitization and safe practices, sterilization and operation theater surgical protocols, teleconsultation, and standard operating COVID-19 practices at various centers. The least number of publications were in cataract and IOL[ 34 ] and oncology[ 27 ] with 3 (1.30%) and 2 (0.86%), respectively, and refractive surgery[ 35 ] and community ophthalmology[ 36 ] with 1 (0.43%) each. The reason being that elective surgeries and community screening in form of camps were at halt for the major part of the year.…”

Section: Discussionmentioning

confidence: 99%

“…Surprisingly, two articles were published related to oncology in the form of practice patterns[ 37 ] and a case report of COVID-19 related to chronic myeloid leukaemia. [ 27 ] A detailed subspecialty-wise distribution of COVID-19 articles during the pandemic is shown in Table 2 and Fig. 2 .…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Intricate scientometric analysis and citation trend of COVID-19-related publications in Indian Journal of Ophthalmology during COVID-19 pandemic

Kaur

Gurnani

2021

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose: To analyze the trend of COVID-19-related publications in the Indian Journal of Ophthalmology (IJO) and assess the specialty wise correlation, distribution, and citation trend during the COVID-19 pandemic. Methods: A retrospective analysis of all COVID-19-related articles was performed from April 2020 to May 2021. The bibliographic records were obtained from the website of IJO, Editor IJO email, and PubMed. The data was then exported as XML into Microsoft access for scientometric analysis. The articles were segregated as Original, Review, Case Report/Series, Letter to the Editor/Commentary, Guest Editorial, PointCounterpoint, Consensus Criteria, Ophthalmic Images, Photo Essay, Surgical Techniques, and All India Ophthalmic Society Meeting Papers. The data was comprehensively analyzed for specialty-wise correlations, distribution, citation trend, and reasons for the same. Results: A total of 231 COVID-19-related articles were published during the study period. The maximum articles were [82 (35.49%)] letters to the editor, followed by [51 (22.08%)] original articles, [30 (12.99%)] commentaries, and [20 (8.66%)] editorials. The least were perspectives, consensus, images, and photo assay with [1 (0.43%)] each. The maximum publications were in July [44 (19.05%)] and least in April [1 (0.43%)]. Considering specialty, the maximum articles were related to general ophthalmology [124 (53.68%)] and least were in refractive surgery and community ophthalmology with [1 (0.43%)] each. The maximum citations were for original articles [352 (34.65%)], which was 2.3 times higher than review articles and letters to editor [150 (14.76%)]. General ophthalmology had 740 (72.83%) citations, which were nearly five times that of cornea [140 (13.78%)]. Conclusion: The IJO showed a trough and crest pattern of COVID-19 publications month wise. Letter to editor and general ophthalmology COVID-19 articles had maximum publications with maximum citations for general ophthalmology owing to practice patterns and COVID-19 challenges.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Intricate scientometric analysis and citation trend of COVID-19-related publications in Indian Journal of Ophthalmology during COVID-19 pandemic

Kaur

Gurnani

2021

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

“…Retinal detachment, retinal hemorrhage, and direct leukemic infiltration of the retina, few cases have reported bilateral blurry vision as the primary presenting symptoms of CML in a young adults. (22,23).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of serum taurine level as a biomarker for early diagnosis and follow up of chronic myeloid leukemia

Alaa M. Shaltoot,

El Agouza IM,

Raafat Abdelfattah

et al. 2023

GSC Biol. Pharm. Sci.

View full text Add to dashboard Cite

Objective: Investigate serum taurine level as a biomarker for early diagnosis and follow up of chronic myeloid leukemia, find correlation between serum taurine level in different phases of Chronic Myeloid Leukemia and number of blast cells in each phase, find correlation between serum taurine level and the percentage of BCR-ABL gene in body which is the diagnostic biomarker for chronic myeloid leukemia. Method: One Hundred and thirty eight chronic myeloid leukemia patients (male and female) were chosen from National Cancer Institute after their approval, patients classified into four groups (Chronic Phase (CP) of CML group, Accelerated Phase (AP) of CML group, Blast Phase (BP) of CML group& after Treatment group (Healing Patients from CML)) according to their Complete clinical examination, investigation and biochemical analysis. Thirty frank healthy control persons enrolled as volunteers. Complete clinical examination, investigation and biochemical analysis (liver and kidney functions, complete blood pictures, Cytology analysis), and the recent biomarker taurine, was measured for all patient and volunteers. Results: The data showed that, according to age, there were statistically significant difference between control group and after treatment group. We did not find a significant difference between gender in different groups (P=0.942).by comparing family history between groups we found that 62.5% of AP group had positive family history, 50% of BP group had positive family history, 44.3% of CP group had positive family history, 33.3% of controls had positive family history while no patients in after treatment group had positive family history .we found that median hemoglobin level were statistically significant differ between groups. By doing pairwise comparison we found that median HB level in AP group is differ from this in CP, after treatment and control group (P=0.027, 0.028, <0.001 respectively). In addition, this in control group is statistically differ from this in BP and CP groups (P=0.002 and <0.001 respectively). That median WBCS level were statistically significant differ between groups. By doing pairwise comparison we found that median WBCS level in after treatment group were differ from CP,AP groups(P=0.012,<0.001 respectively). Also control group differ from CP and AP groups (P=<0.001, <0.001 respectively) .we found that median ALT level were statistically significant differ between groups. By doing pairwise comparison we found that median ALT level in control group is differ from CP and AP (P=0.17, 0.21 respectively).also, median AST level were statistically significant differ between groups. By doing pairwise comparison we found that median AST level in control group is differ from CP and AP and after treatment groups (P=<0.001, <0.001 and 0.034 respectively). Bilirubin and urea were not statistically differ between groups. Creatinine were statistically significant differ between groups. By doing pairwise comparison we found that median creatinine level in control group is differ from AP, BP and CP group (P=<0.001, 0.034, <0.001 respectively). Alkaline phosphatase were statistically significant differ between groups. By doing pairwise comparison we found that median alkaline phosphatase level in control group is differ from AP and CP (P=0.008, <0.001).we found that median blast cells level were statistically significant differ between groups. By doing pairwise comparison we found that median blast cells level in CP group is differ from AP and BP(P=<0.001,<0.001 respectively). Median BCR-ABL level were statistically significant differ between groups. By doing pairwise comparison we found that median BCR-ABL level in CP group is differ from AP and BP (P=<0.001, <0.001 respectively). The most interesting thing that the Median serum taurine level were statistically significant differ between groups. By doing pairwise comparison we found that median taurine level in BP group is differ from CP and after treatment group(P=<0.001,<0.001 respectively) and in AP group is differ from CP, after treatment and control(P=<0.001,<0.001 respectively).we found that there is correlation between taurine level and different numeric variables , we found that age has fair negative correlation with taurine level meaning that for each year increase in age taurine level will decrease .also WBCS has good negative correlation with taurine level meaning that for each increase in in WBCS taurine level will decrease. In addition, RBCS and HB have good positive correlation with taurine level meaning that for each increase in RBCS or HB taurine level will increase. Platelets, neutrophils, bilirubin and urea show no significant correlation with taurine level. ALT and AST show week to fair negative correlation with taurine level. Creatinine has good negative correlation with taurine level. Number of Blast cells and BCR-ABL ratio show excellent negative correlation with taurine level meaning that when they increase taurine level decrease and vice versa . Conclusion: Serum taurine level is statistically significant differ between groups ,that decrease with the increase of the chronicity of disease and the number of blast cells , increase in normal frank control volunteers and after treatment patients which make it possible to be used as a pre biomarker for early diagnosis and follow up of chronic myeloid leukemia disease.

show abstract

Bilateral vision loss as initial presentation of chronic myeloid leukemia in a young adult: A case report and review of the literature

Brown

Kaya

Haymore

et al. 2022

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

Blurring of vision as the only symptom in an undiagnosed case of chronic myeloid leukemia in the COVID-19 era

Cited by 4 publications

References 3 publications

Intricate scientometric analysis and citation trend of COVID-19-related publications in Indian Journal of Ophthalmology during COVID-19 pandemic

Intricate scientometric analysis and citation trend of COVID-19-related publications in Indian Journal of Ophthalmology during COVID-19 pandemic

Evaluation of serum taurine level as a biomarker for early diagnosis and follow up of chronic myeloid leukemia

Bilateral vision loss as initial presentation of chronic myeloid leukemia in a young adult: A case report and review of the literature

Contact Info

Product

Resources

About