BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia

Öztürk, Perihan; Kurutas, Ergul; Ataseven, Arzu; Dokur, Neslihan; Gümüşalan, Yakup; Görür, Ayşegül; Tamer, Lülüfer; Inaloz, Serhat

doi:10.1016/j.jtemb.2014.03.003

Cited by 55 publications

(62 citation statements)

References 18 publications

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“…Vitamin D has direct action on induction of hair growth from the dermal papilla. The role of oxidative stress [42] , nutrients, vitamins [43] , minerals [44,45] , amino acids in maintaining immunity, preventing micro inflammation [46,47] , and promoting hair growth has been discussed by several research scientists. The details of the role of non-androgenic factors have previously been published [48] .…”

Section: Dht Can Be Blocked By Antioxidantsmentioning

confidence: 99%

Controlled clinical trial for evaluation of hair growth with low dose cyclical nutrition therapy in men and women without the use of finasteride

Rajput¹

2017

PAR

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Section: Dht Can Be Blocked By Antioxidantsmentioning

confidence: 99%

Controlled clinical trial for evaluation of hair growth with low dose cyclical nutrition therapy in men and women without the use of finasteride

Rajput¹

2017

PAR

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“…But the common belief, that zinc is also known element associated with the release of the hair and a deficiency of zinc can cause hair loss. [8] In this study, the sample characteristics such as age and the incidence of androgenic alopecia showed that in the alopecia group, agebetween 25-51 years with mean 39.2 years, while in the control group, age between 21-46 years with mean 30.4 years; the results of the analysis of independent t test showed a significant difference (p <0.05). Age in alopecia group are older than the control.…”

Section: Discussionmentioning

confidence: 54%

“…Where the BMI in alopecia group are between 18.1 to 25.0 with a mean of 23.05, while the control ranged from 18.3 to 25.0 with a mean of 22.41 kg/ m 2 . This is according to the study by Otzurk et al (2014), which was done in Turkey to get the BMI of alopecia patients was higher than control, but in that study, they showed significant (p <0.05). In that study, reported that the increasing BMI in patients with androgenic alopecia can cause an imbalance of nutrients that play a role in the pathogenesis of androgenic alopecia.…”

Section: Discussionmentioning

confidence: 75%

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Hair’s Zinc Level on Androgenic Alopecia

Roem¹

2016

AJCEM

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Androgenic alopecia is characterized by progressive loss of hair from the scalp. This research aimed to determine the hair and blood zinc levels in men with androgenic alopecia. The research was conducted in the Departement of Dermatovenereology of Dr. Wahidin Sudirohusodo Hospital, Makassar and the Center for Health Laboratory, Makassar, using the observational research method. The samples comprised 21 males with androgenic alopecia and 11 control samples without androgenic alopecia. The hair and blood of the samples were analyzed using the atomic absorption spectrophotometer receipts. The results showed that there was significant difference (p <0.05) between the levels of androgenic alopecia hair zinc and control. On blood zinc levels found no significant differences between androgenic alopecia and control. Hair zinc levels had a significant relationship with the degree of Hamilton, where the lower the levels of zinc in the hair androgenic alopecia, the greater the degree of Hamilton. However, things are different, between blood zinc levels in hair zinc levels and degrees of Hamilton that there is no significant difference. In this study also found between age and degree of Hamilton, where the increasing age, the greater the degree of Hamilton.

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“…Mn, as a cofactor or activator for many enzymes, is involved in different metabolic pathways through regulation of carbohydrates and lipids metabolism, regulation of blood glucose and cellular energy and participation in synthesis of insulin as well as normal immune functions and the defense mechanisms against free radicals [5] [6]. Many enzymes required Cu ions for their activation, like superoxide dismutase, involved in protection against superoxide radicals and cytochrome oxidase for electron transport [7]. Se appeared to be important antioxidant through its involvement as selenocysteine-containing enzymes as glutathione peroxidase and thioredoxin reductase [8].…”

Section: Introductionmentioning

confidence: 99%

Variations of Hair Trace Element Contents in Diabetic Females

Saleh¹,

Fatani²,

Adly³

et al. 2017

JBM

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Background: Alterations of trace elements, could induce metabolic disorders as they forthwith participating in the metabolic pathways and play different roles modulating it as well as many enzymes require trace elements for their activation and functions. Of these elements, selenium (Se), zinc (Zn), copper (Cu) and manganese (Mn) have been recognized as essentials for metabolism. Hyperglycemia and diabetes mellitus are important causes of mortality and morbidity worldwide, and their global prevalence are growing from 2.8% in 2000 projecting to be 4.4% in 2030. Diabetes is prevalent in Saudi Arabia with high incidence in urbanized areas and its prevalence is estimated to expand 3 times by 2030. Patients and Methods: In total, 75 diabetic women and 80 aberrantly healthy women were recruited. Clinical and familial history was recorded. Hair Se, Zn, Cu and Mn levels were analyzed as well as fasting blood sugar (FBS), glycated hemoglobin (HbA1c). Results: Our findings revealed a marked decrease of Zn and Mn levels in diabetic women hair compared to control group (p < 0.05, p <0.005 respectively). Otherwise, Se and Cu levels were significantly elevated in hair of diabetic patients (p < 0.005, p <0.05 respectively). Conclusion: Diabetes may disrupt the trace elements balance as well as their alterations can affect glucose metabolism and insulin action. Chronic hyperglycemia can cause disturbance of some trace elements which, in turn, can modulate glucose homeostasis. The metabolic dysregulation occurring in hyperglycemia may influence trace element status by increasing excretion, diminishing availability or redistribution of trace elements among different body pools. Hair trace elements can be useful long-term markers for metabolic disturbance; however, larger prospective studies are required to validate their role in diagnosis and follow up applications.

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BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia

Cited by 55 publications

References 18 publications

Controlled clinical trial for evaluation of hair growth with low dose cyclical nutrition therapy in men and women without the use of finasteride

Controlled clinical trial for evaluation of hair growth with low dose cyclical nutrition therapy in men and women without the use of finasteride

Hair’s Zinc Level on Androgenic Alopecia

Variations of Hair Trace Element Contents in Diabetic Females

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