2018
DOI: 10.3866/pku.whxb201803081
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BmmimOAc-Catalyzed Direct Condensation of 2-(Arylamino) Alcohols to Synthesize 3-Arylthiazolidine-2-thiones

Abstract: Thiazolidine-2-thiones have attracted much attention because of their unique bioactivity and have been widely used in the fields of medicine and synthetic heterocyclic chemistry. In this work, a simple and convenient route for the synthesis of 3-arylthiazolidine-2thiones by direct condensation of 2-(arylamino) alcohols with carbon disulfide (CS2) catalyzed by the ionic liquid 1butyl-2,3-dimethylimidazolium acetate (BmmimOAc) has been developed. A series of ionic liquids were used as catalysts in the model reac… Show more

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